Back to Long Tests report for BioC 3.22

This page was generated on 2025-04-26 23:55 -0400 (Sat, 26 Apr 2025).

HostnameOSArch (*)R versionInstalled pkgs
nebbiolo2Linux (Ubuntu 24.04.1 LTS)x86_644.5.0 (2025-04-11) -- "How About a Twenty-Six" 4722
palomino8Windows Server 2022 Datacenterx644.5.0 (2025-04-11 ucrt) -- "How About a Twenty-Six" 4494
lconwaymacOS 12.7.1 Montereyx86_644.5.0 Patched (2025-04-21 r88169) -- "How About a Twenty-Six" 4523
Click on any hostname to see more info about the system (e.g. compilers)      (*) as reported by 'uname -p', except on Windows and Mac OS X

Package 15/30HostnameOS / ArchCHECK
crisprScore 1.13.0  (landing page)
Jean-Philippe Fortin
Snapshot Date: 2025-04-26 09:55 -0400 (Sat, 26 Apr 2025)
git_url: https://git.bioconductor.org/packages/crisprScore
git_branch: devel
git_last_commit: 0f6e423
git_last_commit_date: 2025-04-15 12:44:21 -0400 (Tue, 15 Apr 2025)
nebbiolo2Linux (Ubuntu 24.04.1 LTS) / x86_64  OK  
palomino8Windows Server 2022 Datacenter / x64  ERROR  
lconwaymacOS 12.7.1 Monterey / x86_64  OK  


CHECK results for crisprScore on lconway

To the developers/maintainers of the crisprScore package:
- Use the following Renviron settings to reproduce errors and warnings.
- If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.

raw results


Summary

Package: crisprScore
Version: 1.13.0
Command: /Library/Frameworks/R.framework/Resources/bin/R CMD check --test-dir=longtests --no-stop-on-test-error --no-codoc --no-examples --no-manual --ignore-vignettes --check-subdirs=no crisprScore_1.13.0.tar.gz
StartedAt: 2025-04-26 16:04:33 -0400 (Sat, 26 Apr 2025)
EndedAt: 2025-04-26 16:14:33 -0400 (Sat, 26 Apr 2025)
EllapsedTime: 599.6 seconds
RetCode: 0
Status:   OK  
CheckDir: crisprScore.Rcheck
Warnings: 0

Tests output

crisprScore.Rcheck/tests/testthat.Rout


R version 4.5.0 Patched (2025-04-21 r88169) -- "How About a Twenty-Six"
Copyright (C) 2025 The R Foundation for Statistical Computing
Platform: x86_64-apple-darwin20

R is free software and comes with ABSOLUTELY NO WARRANTY.
You are welcome to redistribute it under certain conditions.
Type 'license()' or 'licence()' for distribution details.

R is a collaborative project with many contributors.
Type 'contributors()' for more information and
'citation()' on how to cite R or R packages in publications.

Type 'demo()' for some demos, 'help()' for on-line help, or
'help.start()' for an HTML browser interface to help.
Type 'q()' to quit R.

> library(testthat)
> library(crisprScore)
Loading required package: crisprScoreData
Loading required package: ExperimentHub
Loading required package: BiocGenerics
Loading required package: generics

Attaching package: 'generics'

The following objects are masked from 'package:base':

    as.difftime, as.factor, as.ordered, intersect, is.element, setdiff,
    setequal, union


Attaching package: 'BiocGenerics'

The following objects are masked from 'package:stats':

    IQR, mad, sd, var, xtabs

The following objects are masked from 'package:base':

    Filter, Find, Map, Position, Reduce, anyDuplicated, aperm, append,
    as.data.frame, basename, cbind, colnames, dirname, do.call,
    duplicated, eval, evalq, get, grep, grepl, is.unsorted, lapply,
    mapply, match, mget, order, paste, pmax, pmax.int, pmin, pmin.int,
    rank, rbind, rownames, sapply, saveRDS, table, tapply, unique,
    unsplit, which.max, which.min

Loading required package: AnnotationHub
Loading required package: BiocFileCache
Loading required package: dbplyr
> 
> test_check("crisprScore")
Channels:
 - bioconda
 - conda-forge
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done

## Package Plan ##

  environment location: /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk

  added / updated specs:
    - python=2.7


The following packages will be downloaded:

    package                    |            build
    ---------------------------|-----------------
    libffi-3.2.1               |                1          41 KB  bioconda
    ------------------------------------------------------------
                                           Total:          41 KB

The following NEW packages will be INSTALLED:

  ca-certificates    conda-forge/noarch::ca-certificates-2025.4.26-hbd8a1cb_0 
  certifi            conda-forge/osx-64::certifi-2019.11.28-py27h8c360ce_1 
  libcxx             conda-forge/osx-64::libcxx-20.1.3-hf95d169_0 
  libffi             bioconda/osx-64::libffi-3.2.1-1 
  libsqlite          conda-forge/osx-64::libsqlite-3.46.0-h1b8f9f3_0 
  libzlib            conda-forge/osx-64::libzlib-1.2.13-h87427d6_6 
  ncurses            conda-forge/osx-64::ncurses-6.5-h0622a9a_3 
  openssl            conda-forge/osx-64::openssl-1.1.1w-h8a1eda9_0 
  pip                conda-forge/noarch::pip-20.1.1-pyh9f0ad1d_0 
  python             conda-forge/osx-64::python-2.7.15-h8e446fc_1011_cpython 
  python_abi         conda-forge/osx-64::python_abi-2.7-1_cp27m 
  readline           conda-forge/osx-64::readline-8.2-h7cca4af_2 
  setuptools         conda-forge/osx-64::setuptools-44.0.0-py27_0 
  sqlite             conda-forge/osx-64::sqlite-3.46.0-h28673e1_0 
  tk                 conda-forge/osx-64::tk-8.6.13-h1abcd95_1 
  wheel              conda-forge/noarch::wheel-0.37.1-pyhd8ed1ab_0 
  zlib               conda-forge/osx-64::zlib-1.2.13-h87427d6_6 


Preparing transaction: ...working... done
Verifying transaction: ...working... done
Executing transaction: ...working... done
Channels:
 - bioconda
 - conda-forge
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done


==> WARNING: A newer version of conda exists. <==
    current version: 24.11.3
    latest version: 25.3.1

Please update conda by running

    $ conda update -n base -c conda-forge conda



# All requested packages already installed.

Channels:
 - bioconda
 - conda-forge
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done


==> WARNING: A newer version of conda exists. <==
    current version: 24.11.3
    latest version: 25.3.1

Please update conda by running

    $ conda update -n base -c conda-forge conda



## Package Plan ##

  environment location: /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk

  added / updated specs:
    - biopython=1.74
    - matplotlib=2.2.3
    - numpy=1.11.3
    - pandas=0.23.4
    - pip=20.1.1
    - python[version='2.7.*,2.7.*']
    - scipy=1.2.1
    - six=1.16.0


The following packages will be downloaded:

    package                    |            build
    ---------------------------|-----------------
    backports-1.0              |     pyhd8ed1ab_3           6 KB  conda-forge
    backports.functools_lru_cache-1.6.1|             py_0           8 KB  conda-forge
    backports_abc-0.5          |             py_1           5 KB  conda-forge
    biopython-1.74             |   py27h0b31af3_0         2.5 MB  conda-forge
    cycler-0.10.0              |             py_2           9 KB  conda-forge
    functools32-3.2.3.2        |             py_3          15 KB  conda-forge
    futures-3.3.0              |   py27h8c360ce_1          25 KB  conda-forge
    kiwisolver-1.1.0           |   py27h5cd23e5_1          57 KB  conda-forge
    libblas-3.8.0              |      14_openblas          10 KB  conda-forge
    libcblas-3.8.0             |      14_openblas          10 KB  conda-forge
    libgfortran-3.0.1          |                0         495 KB  conda-forge
    liblapack-3.8.0            |      14_openblas          10 KB  conda-forge
    libopenblas-0.3.7          |       hd44dcd8_1         8.4 MB  conda-forge
    matplotlib-2.2.3           |           py27_1           6 KB  conda-forge
    matplotlib-base-2.2.3      |   py27hd64abcd_1         6.4 MB  conda-forge
    numpy-1.11.3               |py27hdf140aa_1207         3.5 MB  conda-forge
    pandas-0.23.4              |py27h1702cab_1000         9.1 MB  conda-forge
    pyparsing-2.4.7            |     pyh9f0ad1d_0          60 KB  conda-forge
    python-dateutil-2.8.1      |             py_0         220 KB  conda-forge
    pytz-2020.1                |     pyh9f0ad1d_0         227 KB  conda-forge
    scipy-1.2.1                |   py27hbd7caa9_1        15.7 MB  conda-forge
    singledispatch-3.6.1       |     pyh44b312d_0          12 KB  conda-forge
    subprocess32-3.5.4         |   py27h0b31af3_0          44 KB  conda-forge
    tornado-5.1.1              |py27h1de35cc_1000         642 KB  conda-forge
    ------------------------------------------------------------
                                           Total:        47.4 MB

The following NEW packages will be INSTALLED:

  backports          conda-forge/noarch::backports-1.0-pyhd8ed1ab_3 
  backports.functoo~ conda-forge/noarch::backports.functools_lru_cache-1.6.1-py_0 
  backports_abc      conda-forge/noarch::backports_abc-0.5-py_1 
  biopython          conda-forge/osx-64::biopython-1.74-py27h0b31af3_0 
  cycler             conda-forge/noarch::cycler-0.10.0-py_2 
  freetype           conda-forge/osx-64::freetype-2.12.1-h60636b9_2 
  functools32        conda-forge/noarch::functools32-3.2.3.2-py_3 
  futures            conda-forge/osx-64::futures-3.3.0-py27h8c360ce_1 
  kiwisolver         conda-forge/osx-64::kiwisolver-1.1.0-py27h5cd23e5_1 
  libblas            conda-forge/osx-64::libblas-3.8.0-14_openblas 
  libcblas           conda-forge/osx-64::libcblas-3.8.0-14_openblas 
  libgfortran        conda-forge/osx-64::libgfortran-3.0.1-0 
  liblapack          conda-forge/osx-64::liblapack-3.8.0-14_openblas 
  libopenblas        conda-forge/osx-64::libopenblas-0.3.7-hd44dcd8_1 
  libpng             conda-forge/osx-64::libpng-1.6.43-h92b6c6a_0 
  matplotlib         conda-forge/osx-64::matplotlib-2.2.3-py27_1 
  matplotlib-base    conda-forge/osx-64::matplotlib-base-2.2.3-py27hd64abcd_1 
  numpy              conda-forge/osx-64::numpy-1.11.3-py27hdf140aa_1207 
  pandas             conda-forge/osx-64::pandas-0.23.4-py27h1702cab_1000 
  pyparsing          conda-forge/noarch::pyparsing-2.4.7-pyh9f0ad1d_0 
  python-dateutil    conda-forge/noarch::python-dateutil-2.8.1-py_0 
  pytz               conda-forge/noarch::pytz-2020.1-pyh9f0ad1d_0 
  scipy              conda-forge/osx-64::scipy-1.2.1-py27hbd7caa9_1 
  singledispatch     conda-forge/noarch::singledispatch-3.6.1-pyh44b312d_0 
  six                conda-forge/noarch::six-1.16.0-pyh6c4a22f_0 
  subprocess32       conda-forge/osx-64::subprocess32-3.5.4-py27h0b31af3_0 
  tornado            conda-forge/osx-64::tornado-5.1.1-py27h1de35cc_1000 



Downloading and Extracting Packages: ...working...
scipy-1.2.1          | 15.7 MB   |            |   0% 

pandas-0.23.4        | 9.1 MB    |            |   0% 


libopenblas-0.3.7    | 8.4 MB    |            |   0% 



matplotlib-base-2.2. | 6.4 MB    |            |   0% 




numpy-1.11.3         | 3.5 MB    |            |   0% 





biopython-1.74       | 2.5 MB    |            |   0% 






tornado-5.1.1        | 642 KB    |            |   0% 







libgfortran-3.0.1    | 495 KB    |            |   0% 








pytz-2020.1          | 227 KB    |            |   0% 









python-dateutil-2.8. | 220 KB    |            |   0% 










pyparsing-2.4.7      | 60 KB     |            |   0% 











kiwisolver-1.1.0     | 57 KB     |            |   0% 












subprocess32-3.5.4   | 44 KB     |            |   0% 













futures-3.3.0        | 25 KB     |            |   0% 














functools32-3.2.3.2  | 15 KB     |            |   0% 















singledispatch-3.6.1 | 12 KB     |            |   0% 
















libblas-3.8.0        | 10 KB     |            |   0% 

















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libopenblas-0.3.7    | 8.4 MB    |            |   0% 



matplotlib-base-2.2. | 6.4 MB    |            |   0% 
scipy-1.2.1          | 15.7 MB   | ##8        |  29% 


libopenblas-0.3.7    | 8.4 MB    | ###2       |  33% 



matplotlib-base-2.2. | 6.4 MB    | ###5       |  35% 

pandas-0.23.4        | 9.1 MB    |            |   0% 




numpy-1.11.3         | 3.5 MB    |            |   0% 
scipy-1.2.1          | 15.7 MB   | ######8    |  68% 


libopenblas-0.3.7    | 8.4 MB    | ######2    |  63% 



matplotlib-base-2.2. | 6.4 MB    | #######2   |  72% 

pandas-0.23.4        | 9.1 MB    | #          |  11% 




numpy-1.11.3         | 3.5 MB    | ##8        |  29% 


libopenblas-0.3.7    | 8.4 MB    | #########1 |  92% 



matplotlib-base-2.2. | 6.4 MB    | ########## | 100% 




numpy-1.11.3         | 3.5 MB    | ########## | 100% 


libopenblas-0.3.7    | 8.4 MB    | ########## | 100% 

pandas-0.23.4        | 9.1 MB    | ###8       |  38% 
scipy-1.2.1          | 15.7 MB   | ########## | 100% 
scipy-1.2.1          | 15.7 MB   | ########## | 100% 






tornado-5.1.1        | 642 KB    | 2          |   2% 








pytz-2020.1          | 227 KB    | 7          |   7% 







libgfortran-3.0.1    | 495 KB    | 3          |   3% 








pytz-2020.1          | 227 KB    | ########## | 100% 






tornado-5.1.1        | 642 KB    | ########## | 100% 







libgfortran-3.0.1    | 495 KB    | ########## | 100% 

pandas-0.23.4        | 9.1 MB    | #######7   |  77% 










pyparsing-2.4.7      | 60 KB     | ##6        |  27% 










pyparsing-2.4.7      | 60 KB     | ########## | 100% 











kiwisolver-1.1.0     | 57 KB     | ##7        |  28% 

pandas-0.23.4        | 9.1 MB    | ########## | 100% 











kiwisolver-1.1.0     | 57 KB     | ########## | 100% 









python-dateutil-2.8. | 220 KB    | 7          |   7% 









python-dateutil-2.8. | 220 KB    | ########## | 100% 





biopython-1.74       | 2.5 MB    |            |   1% 












subprocess32-3.5.4   | 44 KB     | ###6       |  36% 














functools32-3.2.3.2  | 15 KB     | ########## | 100% 












subprocess32-3.5.4   | 44 KB     | ########## | 100% 














functools32-3.2.3.2  | 15 KB     | ########## | 100% 













futures-3.3.0        | 25 KB     | ######2    |  63% 













futures-3.3.0        | 25 KB     | ########## | 100% 















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biopython-1.74       | 2.5 MB    | ########## | 100% 

















liblapack-3.8.0      | 10 KB     | ########## | 100% 

















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libblas-3.8.0        | 10 KB     | ########## | 100% 
















libblas-3.8.0        | 10 KB     | ########## | 100% 




numpy-1.11.3         | 3.5 MB    | ########## | 100% 




numpy-1.11.3         | 3.5 MB    | ########## | 100% 



matplotlib-base-2.2. | 6.4 MB    | ########## | 100% 


libopenblas-0.3.7    | 8.4 MB    | ########## | 100% 






tornado-5.1.1        | 642 KB    | ########## | 100% 






tornado-5.1.1        | 642 KB    | ########## | 100% 








pytz-2020.1          | 227 KB    | ########## | 100% 








pytz-2020.1          | 227 KB    | ########## | 100% 










pyparsing-2.4.7      | 60 KB     | ########## | 100% 










pyparsing-2.4.7      | 60 KB     | ########## | 100% 







libgfortran-3.0.1    | 495 KB    | ########## | 100% 







libgfortran-3.0.1    | 495 KB    | ########## | 100% 











kiwisolver-1.1.0     | 57 KB     | ########## | 100% 











kiwisolver-1.1.0     | 57 KB     | ########## | 100% 









python-dateutil-2.8. | 220 KB    | ########## | 100% 









python-dateutil-2.8. | 220 KB    | ########## | 100% 












subprocess32-3.5.4   | 44 KB     | ########## | 100% 












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functools32-3.2.3.2  | 15 KB     | ########## | 100% 













futures-3.3.0        | 25 KB     | ########## | 100% 













futures-3.3.0        | 25 KB     | ########## | 100% 















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biopython-1.74       | 2.5 MB    | ########## | 100% 





biopython-1.74       | 2.5 MB    | ########## | 100% 

















liblapack-3.8.0      | 10 KB     | ########## | 100% 


















libcblas-3.8.0       | 10 KB     | ########## | 100% 
















libblas-3.8.0        | 10 KB     | ########## | 100% 

pandas-0.23.4        | 9.1 MB    | ########## | 100% 
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 done
Preparing transaction: - \ done
Verifying transaction: / - \ | / - \ | / - done
Executing transaction: | / - \ | / - \ | / - \ | / - \ | / - \ | / - \ | / - done
DEPRECATION: Python 2.7 reached the end of its life on January 1st, 2020. Please upgrade your Python as Python 2.7 is no longer maintained. pip 21.0 will drop support for Python 2.7 in January 2021. More details about Python 2 support in pip, can be found at https://pip.pypa.io/en/latest/development/release-process/#python-2-support
Collecting scikit-learn==0.17.1
  Using cached scikit_learn-0.17.1-cp27-cp27m-macosx_10_6_intel.macosx_10_9_intel.macosx_10_9_x86_64.macosx_10_10_intel.macosx_10_10_x86_64.whl (3.9 MB)
Installing collected packages: scikit-learn
Successfully installed scikit-learn-0.17.1
DEPRECATION: Python 2.7 reached the end of its life on January 1st, 2020. Please upgrade your Python as Python 2.7 is no longer maintained. pip 21.0 will drop support for Python 2.7 in January 2021. More details about Python 2 support in pip, can be found at https://pip.pypa.io/en/latest/development/release-process/#python-2-support
Processing /Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/crisprScore/python/azimuth
Requirement already satisfied: scipy<=1.2.1 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from Azimuth==2.0) (1.2.1)
Requirement already satisfied: numpy<=1.14 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from Azimuth==2.0) (1.11.3)
Requirement already satisfied: matplotlib in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from Azimuth==2.0) (2.2.3)
Collecting nose
  Using cached nose-1.3.7-py2-none-any.whl (154 kB)
Requirement already satisfied: scikit-learn<0.18,>=0.17.1 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from Azimuth==2.0) (0.17.1)
Requirement already satisfied: pandas in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from Azimuth==2.0) (0.23.4)
Requirement already satisfied: biopython<=1.76 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from Azimuth==2.0) (1.74)
Requirement already satisfied: cycler>=0.10 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from matplotlib->Azimuth==2.0) (0.10.0)
Requirement already satisfied: pyparsing!=2.0.4,!=2.1.2,!=2.1.6,>=2.0.1 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from matplotlib->Azimuth==2.0) (2.4.7)
Requirement already satisfied: python-dateutil>=2.1 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from matplotlib->Azimuth==2.0) (2.8.1)
Requirement already satisfied: pytz in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from matplotlib->Azimuth==2.0) (2020.1)
Requirement already satisfied: six>=1.10 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from matplotlib->Azimuth==2.0) (1.16.0)
Requirement already satisfied: kiwisolver>=1.0.1 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from matplotlib->Azimuth==2.0) (1.1.0)
Requirement already satisfied: backports.functools_lru_cache in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from matplotlib->Azimuth==2.0) (1.6.1)
Requirement already satisfied: subprocess32 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from matplotlib->Azimuth==2.0) (3.5.4)
Requirement already satisfied: setuptools in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages (from kiwisolver>=1.0.1->matplotlib->Azimuth==2.0) (44.0.0.post20200102)
Building wheels for collected packages: Azimuth
  Building wheel for Azimuth (setup.py): started
  Building wheel for Azimuth (setup.py): finished with status 'done'
  Created wheel for Azimuth: filename=Azimuth-2.0-py2-none-any.whl size=163884 sha256=b4a4b6bbff3c8be9608b36ce586f632f43d48c1a0008608f36682d546c4de541
  Stored in directory: /private/tmp/pip-ephem-wheel-cache-BrDqiP/wheels/98/ad/eb/983169d0f70bb1f2597fe85418a22f6a8ea56c7e0e1a8cd7d8
Successfully built Azimuth
Installing collected packages: nose, Azimuth
Successfully installed Azimuth-2.0 nose-1.3.7
/Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/crisprScore/python/azimuth/azimuth/predict.py:16: UserWarning: 
This call to matplotlib.use() has no effect because the backend has already
been chosen; matplotlib.use() must be called *before* pylab, matplotlib.pyplot,
or matplotlib.backends is imported for the first time.

The backend was *originally* set to 'MacOSX' by the following code:
  File "/Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/crisprScore/python/azimuth/getAzimuth.py", line 4, in <module>
    import azimuth.model_comparison
  File "/Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/crisprScore/python/azimuth/azimuth/model_comparison.py", line 1, in <module>
    import azimuth.predict as pd
  File "/Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/crisprScore/python/azimuth/azimuth/predict.py", line 7, in <module>
    import util
  File "/Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/crisprScore/python/azimuth/azimuth/util.py", line 2, in <module>
    import matplotlib.pylab as plt
  File "/Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages/matplotlib/pylab.py", line 252, in <module>
    from matplotlib import cbook, mlab, pyplot as plt
  File "/Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages/matplotlib/pyplot.py", line 71, in <module>
    from matplotlib.backends import pylab_setup
  File "/Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/azimuth_basilisk/lib/python2.7/site-packages/matplotlib/backends/__init__.py", line 16, in <module>
    line for line in traceback.format_stack()


  matplotlib.use('TkAgg')
Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done

## Package Plan ##

  environment location: /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/deepcpf1_basilisk

  added / updated specs:
    - python=2.7


The following NEW packages will be INSTALLED:

  ca-certificates    conda-forge/noarch::ca-certificates-2025.4.26-hbd8a1cb_0 
  certifi            conda-forge/osx-64::certifi-2019.11.28-py27h8c360ce_1 
  libcxx             conda-forge/osx-64::libcxx-20.1.3-hf95d169_0 
  libffi             conda-forge/osx-64::libffi-3.2.1-hb1e8313_1007 
  libsqlite          conda-forge/osx-64::libsqlite-3.46.0-h1b8f9f3_0 
  libzlib            conda-forge/osx-64::libzlib-1.2.13-h87427d6_6 
  ncurses            conda-forge/osx-64::ncurses-6.5-h0622a9a_3 
  openssl            conda-forge/osx-64::openssl-1.1.1w-h8a1eda9_0 
  pip                conda-forge/noarch::pip-20.1.1-pyh9f0ad1d_0 
  python             conda-forge/osx-64::python-2.7.15-h8e446fc_1011_cpython 
  python_abi         conda-forge/osx-64::python_abi-2.7-1_cp27m 
  readline           conda-forge/osx-64::readline-8.2-h7cca4af_2 
  setuptools         conda-forge/osx-64::setuptools-44.0.0-py27_0 
  sqlite             conda-forge/osx-64::sqlite-3.46.0-h28673e1_0 
  tk                 conda-forge/osx-64::tk-8.6.13-h1abcd95_1 
  wheel              conda-forge/noarch::wheel-0.37.1-pyhd8ed1ab_0 
  zlib               conda-forge/osx-64::zlib-1.2.13-h87427d6_6 


Preparing transaction: ...working... done
Verifying transaction: ...working... done
Executing transaction: ...working... done
Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done


==> WARNING: A newer version of conda exists. <==
    current version: 24.11.3
    latest version: 25.3.1

Please update conda by running

    $ conda update -n base -c conda-forge conda



# All requested packages already installed.

Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done


==> WARNING: A newer version of conda exists. <==
    current version: 24.11.3
    latest version: 25.3.1

Please update conda by running

    $ conda update -n base -c conda-forge conda



# All requested packages already installed.

DEPRECATION: Python 2.7 reached the end of its life on January 1st, 2020. Please upgrade your Python as Python 2.7 is no longer maintained. pip 21.0 will drop support for Python 2.7 in January 2021. More details about Python 2 support in pip, can be found at https://pip.pypa.io/en/latest/development/release-process/#python-2-support
Collecting h5py==2.10.0
  Using cached h5py-2.10.0-cp27-cp27m-macosx_10_6_intel.whl (2.9 MB)
Collecting Keras==2.1.5
  Using cached Keras-2.1.5-py2.py3-none-any.whl (334 kB)
Collecting numpy==1.16.5
  Using cached numpy-1.16.5-cp27-cp27m-macosx_10_9_x86_64.whl (13.9 MB)
Collecting scipy==1.2.1
  Using cached scipy-1.2.1-cp27-cp27m-macosx_10_6_intel.macosx_10_9_intel.macosx_10_9_x86_64.macosx_10_10_intel.macosx_10_10_x86_64.whl (27.4 MB)
Collecting tensorflow==1.0.0
  Using cached tensorflow-1.0.0-cp27-cp27m-macosx_10_11_x86_64.whl (39.3 MB)
Processing /Users/biocbuild/Library/Caches/pip/wheels/3f/57/ee/3a809616477a8502944fc8ac4e2bd464a8d4e28dbe2f2696bb/Theano-1.0.1-py2-none-any.whl
Collecting six
  Using cached six-1.17.0-py2.py3-none-any.whl (11 kB)
Collecting pyyaml
  Using cached PyYAML-5.4.1-cp27-cp27m-macosx_10_9_x86_64.whl (245 kB)
Collecting mock>=2.0.0
  Using cached mock-3.0.5-py2.py3-none-any.whl (25 kB)
Collecting protobuf>=3.1.0
  Using cached protobuf-3.17.3-cp27-cp27m-macosx_10_9_x86_64.whl (1.0 MB)
Requirement already satisfied: wheel in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/deepcpf1_basilisk/lib/python2.7/site-packages (from tensorflow==1.0.0) (0.37.1)
Collecting funcsigs>=1; python_version < "3.3"
  Using cached funcsigs-1.0.2-py2.py3-none-any.whl (17 kB)
Installing collected packages: numpy, six, h5py, scipy, pyyaml, Keras, funcsigs, mock, protobuf, tensorflow, Theano
Successfully installed Keras-2.1.5 Theano-1.0.1 funcsigs-1.0.2 h5py-2.10.0 mock-3.0.5 numpy-1.16.5 protobuf-3.17.3 pyyaml-5.4.1 scipy-1.2.1 six-1.17.0 tensorflow-1.0.0
DEPRECATION: Python 2.7 reached the end of its life on January 1st, 2020. Please upgrade your Python as Python 2.7 is no longer maintained. pip 21.0 will drop support for Python 2.7 in January 2021. More details about Python 2 support in pip, can be found at https://pip.pypa.io/en/latest/development/release-process/#python-2-support
Processing /Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/crisprScore/python/deepcpf1
Building wheels for collected packages: DeepCpf1
  Building wheel for DeepCpf1 (setup.py): started
  Building wheel for DeepCpf1 (setup.py): finished with status 'done'
  Created wheel for DeepCpf1: filename=DeepCpf1-1.0-py2-none-any.whl size=768630 sha256=bfdff9c100ab94963411f90033a896a9e6678dcaf9aeae6f6bfc2b18909632fd
  Stored in directory: /private/tmp/pip-ephem-wheel-cache-9YPq9Q/wheels/7b/84/37/b41dfcb653ed98b329cd632a8c8e9e5789e1d23ea2309ee248
Successfully built DeepCpf1
Installing collected packages: DeepCpf1
Successfully installed DeepCpf1-1.0
Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done

## Package Plan ##

  environment location: /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/enpamgb_basilisk

  added / updated specs:
    - python=3.6


The following packages will be downloaded:

    package                    |            build
    ---------------------------|-----------------
    pip-21.3.1                 |     pyhd8ed1ab_0         1.2 MB  conda-forge
    python-3.6.15              |haf480d7_0_cpython        20.6 MB  conda-forge
    python_abi-3.6             |          2_cp36m           4 KB  conda-forge
    setuptools-58.0.4          |   py36h79c6626_2         960 KB  conda-forge
    ------------------------------------------------------------
                                           Total:        22.8 MB

The following NEW packages will be INSTALLED:

  ca-certificates    conda-forge/noarch::ca-certificates-2025.4.26-hbd8a1cb_0 
  libcxx             conda-forge/osx-64::libcxx-20.1.3-hf95d169_0 
  libffi             conda-forge/osx-64::libffi-3.4.6-h281671d_1 
  liblzma            conda-forge/osx-64::liblzma-5.8.1-hd471939_0 
  liblzma-devel      conda-forge/osx-64::liblzma-devel-5.8.1-hd471939_0 
  libsqlite          conda-forge/osx-64::libsqlite-3.49.1-hdb6dae5_2 
  libzlib            conda-forge/osx-64::libzlib-1.3.1-hd23fc13_2 
  ncurses            conda-forge/osx-64::ncurses-6.5-h0622a9a_3 
  openssl            conda-forge/osx-64::openssl-1.1.1w-h8a1eda9_0 
  pip                conda-forge/noarch::pip-21.3.1-pyhd8ed1ab_0 
  python             conda-forge/osx-64::python-3.6.15-haf480d7_0_cpython 
  python_abi         conda-forge/osx-64::python_abi-3.6-2_cp36m 
  readline           conda-forge/osx-64::readline-8.2-h7cca4af_2 
  setuptools         conda-forge/osx-64::setuptools-58.0.4-py36h79c6626_2 
  sqlite             conda-forge/osx-64::sqlite-3.49.1-h2e4c9dc_2 
  tk                 conda-forge/osx-64::tk-8.6.13-h1abcd95_1 
  wheel              conda-forge/noarch::wheel-0.37.1-pyhd8ed1ab_0 
  xz                 conda-forge/osx-64::xz-5.8.1-h357f2ed_0 
  xz-gpl-tools       conda-forge/osx-64::xz-gpl-tools-5.8.1-h357f2ed_0 
  xz-tools           conda-forge/osx-64::xz-tools-5.8.1-hd471939_0 


Preparing transaction: ...working... done
Verifying transaction: ...working... done
Executing transaction: ...working... done
Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done


==> WARNING: A newer version of conda exists. <==
    current version: 24.11.3
    latest version: 25.3.1

Please update conda by running

    $ conda update -n base -c conda-forge conda



# All requested packages already installed.

Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done


==> WARNING: A newer version of conda exists. <==
    current version: 24.11.3
    latest version: 25.3.1

Please update conda by running

    $ conda update -n base -c conda-forge conda



## Package Plan ##

  environment location: /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/enpamgb_basilisk

  added / updated specs:
    - biopython=1.78
    - h5py=2.10.0
    - keras-preprocessing=1.1.2
    - numpy=1.19.5
    - pandas=1.1.5
    - pip=21.0.1
    - python[version='3.6.*,3.6.*']
    - scikit-learn=0.21.2
    - scipy=1.5.3
    - setuptools=49.6.0
    - six=1.15.0


The following packages will be downloaded:

    package                    |            build
    ---------------------------|-----------------
    biopython-1.78             |   py36hfa26744_2         2.6 MB  conda-forge
    certifi-2021.5.30          |   py36h79c6626_0         141 KB  conda-forge
    h5py-2.10.0                |nompi_py36h4d7a79e_106         923 KB  conda-forge
    joblib-1.2.0               |     pyhd8ed1ab_0         205 KB  conda-forge
    numpy-1.19.5               |   py36h08b5fde_2         5.0 MB  conda-forge
    pandas-1.1.5               |   py36h2be6da3_0        10.0 MB  conda-forge
    pip-21.0.1                 |     pyhd8ed1ab_0         1.1 MB  conda-forge
    pytz-2023.3.post1          |     pyhd8ed1ab_0         183 KB  conda-forge
    scikit-learn-0.21.2        |   py36hd4ffd6c_1         5.9 MB  conda-forge
    scipy-1.5.3                |   py36h4f136de_1        16.9 MB  conda-forge
    setuptools-49.6.0          |   py36h79c6626_3         916 KB  conda-forge
    six-1.15.0                 |     pyh9f0ad1d_0          14 KB  conda-forge
    ------------------------------------------------------------
                                           Total:        43.9 MB

The following NEW packages will be INSTALLED:

  biopython          conda-forge/osx-64::biopython-1.78-py36hfa26744_2 
  c-ares             conda-forge/osx-64::c-ares-1.34.5-hf13058a_0 
  certifi            conda-forge/osx-64::certifi-2021.5.30-py36h79c6626_0 
  h5py               conda-forge/osx-64::h5py-2.10.0-nompi_py36h4d7a79e_106 
  hdf5               conda-forge/osx-64::hdf5-1.10.6-nompi_hc5d9132_1114 
  joblib             conda-forge/noarch::joblib-1.2.0-pyhd8ed1ab_0 
  keras-preprocessi~ conda-forge/noarch::keras-preprocessing-1.1.2-pyhd8ed1ab_0 
  krb5               conda-forge/osx-64::krb5-1.20.1-h0165f36_0 
  libblas            conda-forge/osx-64::libblas-3.9.0-20_osx64_openblas 
  libcblas           conda-forge/osx-64::libcblas-3.9.0-20_osx64_openblas 
  libcurl            conda-forge/osx-64::libcurl-7.87.0-haf73cf8_0 
  libedit            conda-forge/osx-64::libedit-3.1.20250104-pl5321ha958ccf_0 
  libev              conda-forge/osx-64::libev-4.33-h10d778d_2 
  libgfortran        conda-forge/osx-64::libgfortran-14.2.0-hef36b68_105 
  libgfortran5       conda-forge/osx-64::libgfortran5-14.2.0-h58528f3_105 
  liblapack          conda-forge/osx-64::liblapack-3.9.0-20_osx64_openblas 
  libnghttp2         conda-forge/osx-64::libnghttp2-1.51.0-h0dd9d14_0 
  libopenblas        conda-forge/osx-64::libopenblas-0.3.25-openmp_hfef2a42_0 
  libssh2            conda-forge/osx-64::libssh2-1.10.0-h7535e13_3 
  llvm-openmp        conda-forge/osx-64::llvm-openmp-20.1.3-ha54dae1_0 
  numpy              conda-forge/osx-64::numpy-1.19.5-py36h08b5fde_2 
  pandas             conda-forge/osx-64::pandas-1.1.5-py36h2be6da3_0 
  python-dateutil    conda-forge/noarch::python-dateutil-2.8.2-pyhd8ed1ab_0 
  pytz               conda-forge/noarch::pytz-2023.3.post1-pyhd8ed1ab_0 
  scikit-learn       conda-forge/osx-64::scikit-learn-0.21.2-py36hd4ffd6c_1 
  scipy              conda-forge/osx-64::scipy-1.5.3-py36h4f136de_1 
  six                conda-forge/noarch::six-1.15.0-pyh9f0ad1d_0 
  zlib               conda-forge/osx-64::zlib-1.2.13-h87427d6_6 

The following packages will be DOWNGRADED:

  libsqlite                               3.49.1-hdb6dae5_2 --> 3.46.0-h1b8f9f3_0 
  libzlib                                  1.3.1-hd23fc13_2 --> 1.2.13-h87427d6_6 
  pip                                   21.3.1-pyhd8ed1ab_0 --> 21.0.1-pyhd8ed1ab_0 
  setuptools                          58.0.4-py36h79c6626_2 --> 49.6.0-py36h79c6626_3 
  sqlite                                  3.49.1-h2e4c9dc_2 --> 3.46.0-h28673e1_0 



Downloading and Extracting Packages: ...working...
scipy-1.5.3          | 16.9 MB   |            |   0% 

pandas-1.1.5         | 10.0 MB   |            |   0% 


scikit-learn-0.21.2  | 5.9 MB    |            |   0% 



numpy-1.19.5         | 5.0 MB    |            |   0% 




biopython-1.78       | 2.6 MB    |            |   0% 





pip-21.0.1           | 1.1 MB    |            |   0% 






h5py-2.10.0          | 923 KB    |            |   0% 







setuptools-49.6.0    | 916 KB    |            |   0% 








joblib-1.2.0         | 205 KB    |            |   0% 









pytz-2023.3.post1    | 183 KB    |            |   0% 










certifi-2021.5.30    | 141 KB    |            |   0% 











six-1.15.0           | 14 KB     |            |   0% 

pandas-1.1.5         | 10.0 MB   | 2          |   2% 
scipy-1.5.3          | 16.9 MB   |            |   1% 



numpy-1.19.5         | 5.0 MB    |            |   0% 

pandas-1.1.5         | 10.0 MB   | #####9     |  60% 
scipy-1.5.3          | 16.9 MB   | ##6        |  26% 



numpy-1.19.5         | 5.0 MB    | ##2        |  22% 




biopython-1.78       | 2.6 MB    |            |   1% 


scikit-learn-0.21.2  | 5.9 MB    |            |   0% 

pandas-1.1.5         | 10.0 MB   | ########## | 100% 

pandas-1.1.5         | 10.0 MB   | ########## | 100% 
scipy-1.5.3          | 16.9 MB   | ####1      |  41% 



numpy-1.19.5         | 5.0 MB    | ########## | 100% 



numpy-1.19.5         | 5.0 MB    | ########## | 100% 





pip-21.0.1           | 1.1 MB    | 1          |   1% 




biopython-1.78       | 2.6 MB    | #######5   |  76% 


scikit-learn-0.21.2  | 5.9 MB    | ######4    |  64% 





pip-21.0.1           | 1.1 MB    | ########## | 100% 
scipy-1.5.3          | 16.9 MB   | ######4    |  64% 




biopython-1.78       | 2.6 MB    | ########## | 100% 







setuptools-49.6.0    | 916 KB    | 1          |   2% 








joblib-1.2.0         | 205 KB    | 7          |   8% 
scipy-1.5.3          | 16.9 MB   | ########9  |  89% 







setuptools-49.6.0    | 916 KB    | ########## | 100% 


scikit-learn-0.21.2  | 5.9 MB    | ########## | 100% 


scikit-learn-0.21.2  | 5.9 MB    | ########## | 100% 








joblib-1.2.0         | 205 KB    | ########## | 100% 






h5py-2.10.0          | 923 KB    | 1          |   2% 









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                                                      done
Preparing transaction: - done
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Building wheels for collected packages: wrapt
  Building wheel for wrapt (setup.py): started
  Building wheel for wrapt (setup.py): finished with status 'done'
  Created wheel for wrapt: filename=wrapt-1.12.1-cp36-cp36m-macosx_11_0_x86_64.whl size=32713 sha256=2adb22460e6c1299bec110764e09bb0d5faae1065b8ff58a7cf2b836d1b7e9b8
  Stored in directory: /Users/biocbuild/Library/Caches/pip/wheels/32/42/7f/23cae9ff6ef66798d00dc5d659088e57dbba01566f6c60db63
Successfully built wrapt
Installing collected packages: urllib3, pyasn1, idna, charset-normalizer, zipp, typing-extensions, rsa, requests, pyasn1-modules, oauthlib, cachetools, requests-oauthlib, importlib-metadata, google-auth, dataclasses, werkzeug, tensorboard-plugin-wit, tensorboard-data-server, protobuf, markdown, grpcio, google-auth-oauthlib, absl-py, wrapt, termcolor, tensorflow-estimator, tensorboard, opt-einsum, google-pasta, gast, flatbuffers, astunparse, tensorflow
Successfully installed absl-py-0.15.0 astunparse-1.6.3 cachetools-4.2.4 charset-normalizer-2.0.12 dataclasses-0.8 flatbuffers-1.12 gast-0.3.3 google-auth-2.22.0 google-auth-oauthlib-0.4.6 google-pasta-0.2.0 grpcio-1.32.0 idna-3.10 importlib-metadata-4.8.3 markdown-3.3.7 oauthlib-3.2.2 opt-einsum-3.3.0 protobuf-3.19.6 pyasn1-0.5.1 pyasn1-modules-0.3.0 requests-2.27.1 requests-oauthlib-2.0.0 rsa-4.9.1 tensorboard-2.10.1 tensorboard-data-server-0.6.1 tensorboard-plugin-wit-1.8.1 tensorflow-2.4.1 tensorflow-estimator-2.4.0 termcolor-1.1.0 typing-extensions-3.7.4.3 urllib3-1.26.20 werkzeug-2.0.3 wrapt-1.12.1 zipp-3.6.0
Processing /Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/crisprScore/python/enpamgb
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Requirement already satisfied: requests-oauthlib>=0.7.0 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/enpamgb_basilisk/lib/python3.6/site-packages (from google-auth-oauthlib<0.5,>=0.4.1->tensorboard~=2.4->tensorflow>=1.14.0->sgrna-modeler==0.1.0) (2.0.0)
Requirement already satisfied: importlib-metadata>=4.4 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/enpamgb_basilisk/lib/python3.6/site-packages (from markdown>=2.6.8->tensorboard~=2.4->tensorflow>=1.14.0->sgrna-modeler==0.1.0) (4.8.3)
Requirement already satisfied: zipp>=0.5 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/enpamgb_basilisk/lib/python3.6/site-packages (from importlib-metadata>=4.4->markdown>=2.6.8->tensorboard~=2.4->tensorflow>=1.14.0->sgrna-modeler==0.1.0) (3.6.0)
Requirement already satisfied: pyasn1<0.6.0,>=0.4.6 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/enpamgb_basilisk/lib/python3.6/site-packages (from pyasn1-modules>=0.2.1->google-auth<3,>=1.6.3->tensorboard~=2.4->tensorflow>=1.14.0->sgrna-modeler==0.1.0) (0.5.1)
Requirement already satisfied: charset-normalizer~=2.0.0 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/enpamgb_basilisk/lib/python3.6/site-packages (from requests<3,>=2.21.0->tensorboard~=2.4->tensorflow>=1.14.0->sgrna-modeler==0.1.0) (2.0.12)
Requirement already satisfied: certifi>=2017.4.17 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/enpamgb_basilisk/lib/python3.6/site-packages (from requests<3,>=2.21.0->tensorboard~=2.4->tensorflow>=1.14.0->sgrna-modeler==0.1.0) (2021.5.30)
Requirement already satisfied: idna<4,>=2.5 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/enpamgb_basilisk/lib/python3.6/site-packages (from requests<3,>=2.21.0->tensorboard~=2.4->tensorflow>=1.14.0->sgrna-modeler==0.1.0) (3.10)
Requirement already satisfied: oauthlib>=3.0.0 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/enpamgb_basilisk/lib/python3.6/site-packages (from requests-oauthlib>=0.7.0->google-auth-oauthlib<0.5,>=0.4.1->tensorboard~=2.4->tensorflow>=1.14.0->sgrna-modeler==0.1.0) (3.2.2)
Requirement already satisfied: dataclasses in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/enpamgb_basilisk/lib/python3.6/site-packages (from werkzeug>=1.0.1->tensorboard~=2.4->tensorflow>=1.14.0->sgrna-modeler==0.1.0) (0.8)
Building wheels for collected packages: sgrna-modeler
  Building wheel for sgrna-modeler (setup.py): started
  Building wheel for sgrna-modeler (setup.py): finished with status 'done'
  Created wheel for sgrna-modeler: filename=sgrna_modeler-0.1.0-py3-none-any.whl size=459415 sha256=6906bee2c7c7e5de8bb6b7c191e0848eb7574a3d8f4c9a3460b0ae07c55e1f3c
  Stored in directory: /private/tmp/pip-ephem-wheel-cache-y67equ4b/wheels/37/2e/fc/bee98ee2abca5a7c383d760ea51b57e35297cf3107424d7a06
Successfully built sgrna-modeler
Installing collected packages: sgrna-modeler
Successfully installed sgrna-modeler-0.1.0
Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done

## Package Plan ##

  environment location: /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/lindel_basilisk

  added / updated specs:
    - python=3.6


The following NEW packages will be INSTALLED:

  ca-certificates    conda-forge/noarch::ca-certificates-2025.4.26-hbd8a1cb_0 
  libcxx             conda-forge/osx-64::libcxx-20.1.3-hf95d169_0 
  libffi             conda-forge/osx-64::libffi-3.4.6-h281671d_1 
  liblzma            conda-forge/osx-64::liblzma-5.8.1-hd471939_0 
  liblzma-devel      conda-forge/osx-64::liblzma-devel-5.8.1-hd471939_0 
  libsqlite          conda-forge/osx-64::libsqlite-3.49.1-hdb6dae5_2 
  libzlib            conda-forge/osx-64::libzlib-1.3.1-hd23fc13_2 
  ncurses            conda-forge/osx-64::ncurses-6.5-h0622a9a_3 
  openssl            conda-forge/osx-64::openssl-1.1.1w-h8a1eda9_0 
  pip                conda-forge/noarch::pip-21.3.1-pyhd8ed1ab_0 
  python             conda-forge/osx-64::python-3.6.15-haf480d7_0_cpython 
  python_abi         conda-forge/osx-64::python_abi-3.6-2_cp36m 
  readline           conda-forge/osx-64::readline-8.2-h7cca4af_2 
  setuptools         conda-forge/osx-64::setuptools-58.0.4-py36h79c6626_2 
  sqlite             conda-forge/osx-64::sqlite-3.49.1-h2e4c9dc_2 
  tk                 conda-forge/osx-64::tk-8.6.13-h1abcd95_1 
  wheel              conda-forge/noarch::wheel-0.37.1-pyhd8ed1ab_0 
  xz                 conda-forge/osx-64::xz-5.8.1-h357f2ed_0 
  xz-gpl-tools       conda-forge/osx-64::xz-gpl-tools-5.8.1-h357f2ed_0 
  xz-tools           conda-forge/osx-64::xz-tools-5.8.1-hd471939_0 


Preparing transaction: ...working... done
Verifying transaction: ...working... done
Executing transaction: ...working... done
Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done


==> WARNING: A newer version of conda exists. <==
    current version: 24.11.3
    latest version: 25.3.1

Please update conda by running

    $ conda update -n base -c conda-forge conda



# All requested packages already installed.

Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done


==> WARNING: A newer version of conda exists. <==
    current version: 24.11.3
    latest version: 25.3.1

Please update conda by running

    $ conda update -n base -c conda-forge conda



## Package Plan ##

  environment location: /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/lindel_basilisk

  added / updated specs:
    - numpy=1.19.5
    - pip=21.0.1
    - python[version='3.6.*,3.6.*']
    - scipy=1.5.3


The following NEW packages will be INSTALLED:

  libblas            conda-forge/osx-64::libblas-3.9.0-20_osx64_openblas 
  libcblas           conda-forge/osx-64::libcblas-3.9.0-20_osx64_openblas 
  libgfortran        conda-forge/osx-64::libgfortran-14.2.0-hef36b68_105 
  libgfortran5       conda-forge/osx-64::libgfortran5-14.2.0-h58528f3_105 
  liblapack          conda-forge/osx-64::liblapack-3.9.0-20_osx64_openblas 
  libopenblas        conda-forge/osx-64::libopenblas-0.3.25-openmp_hfef2a42_0 
  llvm-openmp        conda-forge/osx-64::llvm-openmp-20.1.3-ha54dae1_0 
  numpy              conda-forge/osx-64::numpy-1.19.5-py36h08b5fde_2 
  scipy              conda-forge/osx-64::scipy-1.5.3-py36h4f136de_1 

The following packages will be DOWNGRADED:

  pip                                   21.3.1-pyhd8ed1ab_0 --> 21.0.1-pyhd8ed1ab_0 



Downloading and Extracting Packages: ...working... done
Preparing transaction: - done
Verifying transaction: | / - \ | / done
Executing transaction: \ | / - \ | / - \ | / - \ | / - \ | / - \ | / - \ | done
Processing /Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/crisprScore/python/lindel
Requirement already satisfied: numpy in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/lindel_basilisk/lib/python3.6/site-packages (from Lindel==1.0) (1.19.5)
Requirement already satisfied: scipy in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/lindel_basilisk/lib/python3.6/site-packages (from Lindel==1.0) (1.5.3)
Building wheels for collected packages: Lindel
  Building wheel for Lindel (setup.py): started
  Building wheel for Lindel (setup.py): finished with status 'done'
  Created wheel for Lindel: filename=Lindel-1.0-py3-none-any.whl size=33618 sha256=74cd8915628c8bf21c2928fc763b718f9229291b7c3fb605c3e83aa4fc65dd7a
  Stored in directory: /private/tmp/pip-ephem-wheel-cache-6rgmelgw/wheels/5e/4c/b5/63d0510bb10b7087aa0d2eaef0bde61197195ccb4a46a84816
Successfully built Lindel
Installing collected packages: Lindel
Successfully installed Lindel-1.0
Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done

## Package Plan ##

  environment location: /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/deephf_basilisk

  added / updated specs:
    - python=3.6


The following NEW packages will be INSTALLED:

  ca-certificates    conda-forge/noarch::ca-certificates-2025.4.26-hbd8a1cb_0 
  libcxx             conda-forge/osx-64::libcxx-20.1.3-hf95d169_0 
  libffi             conda-forge/osx-64::libffi-3.4.6-h281671d_1 
  liblzma            conda-forge/osx-64::liblzma-5.8.1-hd471939_0 
  liblzma-devel      conda-forge/osx-64::liblzma-devel-5.8.1-hd471939_0 
  libsqlite          conda-forge/osx-64::libsqlite-3.49.1-hdb6dae5_2 
  libzlib            conda-forge/osx-64::libzlib-1.3.1-hd23fc13_2 
  ncurses            conda-forge/osx-64::ncurses-6.5-h0622a9a_3 
  openssl            conda-forge/osx-64::openssl-1.1.1w-h8a1eda9_0 
  pip                conda-forge/noarch::pip-21.3.1-pyhd8ed1ab_0 
  python             conda-forge/osx-64::python-3.6.15-haf480d7_0_cpython 
  python_abi         conda-forge/osx-64::python_abi-3.6-2_cp36m 
  readline           conda-forge/osx-64::readline-8.2-h7cca4af_2 
  setuptools         conda-forge/osx-64::setuptools-58.0.4-py36h79c6626_2 
  sqlite             conda-forge/osx-64::sqlite-3.49.1-h2e4c9dc_2 
  tk                 conda-forge/osx-64::tk-8.6.13-h1abcd95_1 
  wheel              conda-forge/noarch::wheel-0.37.1-pyhd8ed1ab_0 
  xz                 conda-forge/osx-64::xz-5.8.1-h357f2ed_0 
  xz-gpl-tools       conda-forge/osx-64::xz-gpl-tools-5.8.1-h357f2ed_0 
  xz-tools           conda-forge/osx-64::xz-tools-5.8.1-hd471939_0 


Preparing transaction: ...working... done
Verifying transaction: ...working... done
Executing transaction: ...working... done
Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done


==> WARNING: A newer version of conda exists. <==
    current version: 24.11.3
    latest version: 25.3.1

Please update conda by running

    $ conda update -n base -c conda-forge conda



# All requested packages already installed.

Channels:
 - conda-forge
 - bioconda
Platform: osx-64
Collecting package metadata (repodata.json): ...working... done
Solving environment: ...working... done


==> WARNING: A newer version of conda exists. <==
    current version: 24.11.3
    latest version: 25.3.1

Please update conda by running

    $ conda update -n base -c conda-forge conda



## Package Plan ##

  environment location: /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/deephf_basilisk

  added / updated specs:
    - python[version='3.6.*,3.6.*']
    - viennarna=2.4.5


The following packages will be downloaded:

    package                    |            build
    ---------------------------|-----------------
    viennarna-2.4.5            |       hd28b015_3        13.9 MB  bioconda
    ------------------------------------------------------------
                                           Total:        13.9 MB

The following NEW packages will be INSTALLED:

  viennarna          bioconda/osx-64::viennarna-2.4.5-hd28b015_3 
  zlib               conda-forge/osx-64::zlib-1.2.13-h87427d6_6 

The following packages will be DOWNGRADED:

  libsqlite                               3.49.1-hdb6dae5_2 --> 3.46.0-h1b8f9f3_0 
  libzlib                                  1.3.1-hd23fc13_2 --> 1.2.13-h87427d6_6 
  sqlite                                  3.49.1-h2e4c9dc_2 --> 3.46.0-h28673e1_0 



Downloading and Extracting Packages: ...working...
viennarna-2.4.5      | 13.9 MB   |            |   0% 
viennarna-2.4.5      | 13.9 MB   |            |   0% 
viennarna-2.4.5      | 13.9 MB   | ######3    |  64% 
viennarna-2.4.5      | 13.9 MB   | ########## | 100% 
viennarna-2.4.5      | 13.9 MB   | ########## | 100% 
                                                     
 done
Preparing transaction: - done
Verifying transaction: | done
Executing transaction: - done
Collecting biopython==1.71
  Using cached biopython-1.71-cp36-cp36m-macosx_10_6_intel.macosx_10_9_intel.macosx_10_9_x86_64.macosx_10_10_intel.macosx_10_10_x86_64.whl (2.1 MB)
Collecting h5py==2.9.0
  Using cached h5py-2.9.0-cp36-cp36m-macosx_10_6_intel.macosx_10_9_intel.macosx_10_9_x86_64.macosx_10_10_intel.macosx_10_10_x86_64.whl (6.3 MB)
Collecting dotmap==1.2.20
  Using cached dotmap-1.2.20-py3-none-any.whl
Collecting numpy==1.14.0
  Using cached numpy-1.14.0-cp36-cp36m-macosx_10_6_intel.macosx_10_9_intel.macosx_10_9_x86_64.macosx_10_10_intel.macosx_10_10_x86_64.whl (4.7 MB)
Collecting scipy==1.1.0
  Using cached scipy-1.1.0-cp36-cp36m-macosx_10_6_intel.macosx_10_9_intel.macosx_10_9_x86_64.macosx_10_10_intel.macosx_10_10_x86_64.whl (16.7 MB)
Collecting pandas==0.25.3
  Using cached pandas-0.25.3-cp36-cp36m-macosx_10_9_x86_64.whl (10.4 MB)
Collecting Keras==2.1.6
  Using cached Keras-2.1.6-py2.py3-none-any.whl (339 kB)
Collecting gpy==1.9.8
  Using cached GPy-1.9.8-cp36-cp36m-macosx_10_7_x86_64.whl (1.5 MB)
Collecting scikit-learn==0.19.1
  Using cached scikit_learn-0.19.1-cp36-cp36m-macosx_10_6_intel.macosx_10_9_intel.macosx_10_9_x86_64.macosx_10_10_intel.macosx_10_10_x86_64.whl (7.6 MB)
Collecting matplotlib==3.1.1
  Using cached matplotlib-3.1.1-cp36-cp36m-macosx_10_6_intel.macosx_10_9_intel.macosx_10_9_x86_64.macosx_10_10_intel.macosx_10_10_x86_64.whl (14.4 MB)
Collecting tensorboard==1.8.0
  Using cached tensorboard-1.8.0-py3-none-any.whl (3.1 MB)
Collecting tensorflow==1.8.0
  Using cached tensorflow-1.8.0-cp36-cp36m-macosx_10_11_x86_64.whl (46.5 MB)
Collecting Theano==1.0.5
  Using cached Theano-1.0.5-py3-none-any.whl
Collecting six
  Using cached six-1.17.0-py2.py3-none-any.whl (11 kB)
Collecting python-dateutil>=2.6.1
  Using cached python_dateutil-2.9.0.post0-py2.py3-none-any.whl (229 kB)
Collecting pytz>=2017.2
  Using cached pytz-2025.2-py2.py3-none-any.whl (509 kB)
Collecting pyyaml
  Using cached PyYAML-6.0.1-cp36-cp36m-macosx_10_9_x86_64.whl (189 kB)
Collecting paramz>=0.9.0
  Using cached paramz-0.9.6-py3-none-any.whl (103 kB)
Collecting cycler>=0.10
  Using cached cycler-0.11.0-py3-none-any.whl (6.4 kB)
Collecting pyparsing!=2.0.4,!=2.1.2,!=2.1.6,>=2.0.1
  Using cached pyparsing-3.1.4-py3-none-any.whl (104 kB)
Collecting kiwisolver>=1.0.1
  Using cached kiwisolver-1.3.1-cp36-cp36m-macosx_10_9_x86_64.whl (61 kB)
Collecting protobuf>=3.4.0
  Using cached protobuf-3.19.6-cp36-cp36m-macosx_10_9_x86_64.whl (979 kB)
Collecting html5lib==0.9999999
  Using cached html5lib-0.9999999-py3-none-any.whl
Collecting bleach==1.5.0
  Using cached bleach-1.5.0-py2.py3-none-any.whl (17 kB)
Requirement already satisfied: wheel>=0.26 in /Users/biocbuild/Library/Caches/org.R-project.R/R/basilisk/1.21.0/crisprScore/1.13.0/deephf_basilisk/lib/python3.6/site-packages (from tensorboard==1.8.0) (0.37.1)
Collecting markdown>=2.6.8
  Using cached Markdown-3.3.7-py3-none-any.whl (97 kB)
Collecting werkzeug>=0.11.10
  Using cached Werkzeug-2.0.3-py3-none-any.whl (289 kB)
Collecting grpcio>=1.8.6
  Using cached grpcio-1.48.2-cp36-cp36m-macosx_10_10_x86_64.whl (4.4 MB)
Collecting termcolor>=1.1.0
  Using cached termcolor-1.1.0-py3-none-any.whl
Collecting astor>=0.6.0
  Using cached astor-0.8.1-py2.py3-none-any.whl (27 kB)
Collecting absl-py>=0.1.6
  Using cached absl_py-1.4.0-py3-none-any.whl (126 kB)
Collecting gast>=0.2.0
  Using cached gast-0.6.0-py3-none-any.whl (21 kB)
Collecting importlib-metadata>=4.4
  Using cached importlib_metadata-4.8.3-py3-none-any.whl (17 kB)
Collecting decorator>=4.0.10
  Using cached decorator-5.1.1-py3-none-any.whl (9.1 kB)
Collecting dataclasses
  Using cached dataclasses-0.8-py3-none-any.whl (19 kB)
Collecting typing-extensions>=3.6.4
  Using cached typing_extensions-4.1.1-py3-none-any.whl (26 kB)
Collecting zipp>=0.5
  Using cached zipp-3.6.0-py3-none-any.whl (5.3 kB)
Installing collected packages: zipp, typing-extensions, six, numpy, importlib-metadata, html5lib, dataclasses, werkzeug, scipy, protobuf, markdown, decorator, bleach, termcolor, tensorboard, pyyaml, pytz, python-dateutil, pyparsing, paramz, kiwisolver, h5py, grpcio, gast, cycler, astor, absl-py, Theano, tensorflow, scikit-learn, pandas, matplotlib, Keras, gpy, dotmap, biopython
Successfully installed Keras-2.1.6 Theano-1.0.5 absl-py-1.4.0 astor-0.8.1 biopython-1.71 bleach-1.5.0 cycler-0.11.0 dataclasses-0.8 decorator-5.1.1 dotmap-1.2.20 gast-0.6.0 gpy-1.9.8 grpcio-1.48.2 h5py-2.9.0 html5lib-0.9999999 importlib-metadata-4.8.3 kiwisolver-1.3.1 markdown-3.3.7 matplotlib-3.1.1 numpy-1.14.0 pandas-0.25.3 paramz-0.9.6 protobuf-3.19.6 pyparsing-3.1.4 python-dateutil-2.9.0.post0 pytz-2025.2 pyyaml-6.0.1 scikit-learn-0.19.1 scipy-1.1.0 six-1.17.0 tensorboard-1.8.0 tensorflow-1.8.0 termcolor-1.1.0 typing-extensions-4.1.1 werkzeug-2.0.3 zipp-3.6.0
Processing /Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/crisprScore/python/deephf
  Preparing metadata (setup.py): started
  Preparing metadata (setup.py): finished with status 'done'
Building wheels for collected packages: DeepHF
  Building wheel for DeepHF (setup.py): started
  Building wheel for DeepHF (setup.py): finished with status 'done'
  Created wheel for DeepHF: filename=DeepHF-1.0-py3-none-any.whl size=10512 sha256=a1b846d957528c567733956b1839cda1f3ab2c141468ccfdf18101cb0a60c529
  Stored in directory: /private/tmp/pip-ephem-wheel-cache-bepf_lvu/wheels/05/09/f3/ec8da7161c142810fa90fb40805b44fe164bda7c4d892675e3
Successfully built DeepHF
Installing collected packages: DeepHF
Successfully installed DeepHF-1.0
[ FAIL 0 | WARN 10 | SKIP 0 | PASS 8 ]

[ FAIL 0 | WARN 10 | SKIP 0 | PASS 8 ]
> 
> proc.time()
   user  system elapsed 
208.342 100.336 505.479 

'R CMD check' output

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### Running command:
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###   /Library/Frameworks/R.framework/Resources/bin/R CMD check --test-dir=longtests --no-stop-on-test-error --no-codoc --no-examples --no-manual --ignore-vignettes --check-subdirs=no crisprScore_1.13.0.tar.gz
###
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* using log directory ‘/Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck’
* using R version 4.5.0 Patched (2025-04-21 r88169)
* using platform: x86_64-apple-darwin20
* R was compiled by
    Apple clang version 14.0.0 (clang-1400.0.29.202)
    GNU Fortran (GCC) 14.2.0
* running under: macOS Monterey 12.7.6
* using session charset: UTF-8
* using options ‘--no-codoc --no-examples --no-manual --ignore-vignettes --no-stop-on-test-error’
* checking for file ‘crisprScore/DESCRIPTION’ ... OK
* this is package ‘crisprScore’ version ‘1.13.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... OK
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... NOTE
Found the following non-portable file paths:
  crisprScore/inst/python/deepspcas9/DeepCas9_Final/PreTrain-Final-False-3-5-7-100-70-40-0.001-550-True-80-60.data-00000-of-00001
  crisprScore/inst/python/deepspcas9/DeepCas9_Final/PreTrain-Final-False-3-5-7-100-70-40-0.001-550-True-80-60.index
  crisprScore/inst/python/deepspcas9/DeepCas9_Final/PreTrain-Final-False-3-5-7-100-70-40-0.001-550-True-80-60.meta

Tarballs are only required to store paths of up to 100 bytes and cannot
store those of more than 256 bytes, with restrictions including to 100
bytes for the final component.
See section ‘Package structure’ in the ‘Writing R Extensions’ manual.
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘crisprScore’ can be installed ... NOTE
Found the following notes/warnings:
  Non-staged installation was used
See ‘/Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/00install.out’ for details.
* checking installed package size ... INFO
  installed size is  7.2Mb
  sub-directories of 1Mb or more:
    python   5.9Mb
* checking package directory ... OK
* checking DESCRIPTION meta-information ... NOTE
License stub is invalid DCF.
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking whether startup messages can be suppressed ... OK
* checking dependencies in R code ... NOTE
':::' call which should be '::': ‘basilisk.utils:::getPythonBinary’
  See the note in ?`:::` about the use of this operator.
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... OK
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... SKIPPED
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking contents of ‘data’ directory ... OK
* checking data for non-ASCII characters ... OK
* checking LazyData ... OK
* checking data for ASCII and uncompressed saves ... OK
* checking R/sysdata.rda ... OK
* checking line endings in shell scripts ... OK
* checking line endings in Makefiles ... OK
* checking for GNU extensions in Makefiles ... OK
* checking include directives in Makefiles ... OK
* checking files in ‘vignettes’ ... SKIPPED
* checking examples ... SKIPPED
* checking for unstated dependencies in ‘longtests’ ... OK
* checking tests in ‘longtests’ ...
  Running ‘testthat.R’
 OK
* DONE

Status: 4 NOTEs
See
  ‘/Users/biocbuild/bbs-3.22-bioc-longtests/meat/crisprScore.Rcheck/00check.log’
for details.


Installation output

crisprScore.Rcheck/00install.out

* installing *source* package ‘crisprScore’ ...
** this is package ‘crisprScore’ version ‘1.13.0’
** using non-staged installation via StagedInstall field
** R
** data
*** moving datasets to lazyload DB
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
** building package indices
** installing vignettes
** testing if installed package can be loaded
* DONE (crisprScore)