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This page was generated on 2025-04-24 13:02 -0400 (Thu, 24 Apr 2025).

HostnameOSArch (*)R versionInstalled pkgs
nebbiolo1Linux (Ubuntu 24.04.1 LTS)x86_644.5.0 RC (2025-04-04 r88126) -- "How About a Twenty-Six" 4831
palomino7Windows Server 2022 Datacenterx644.5.0 RC (2025-04-04 r88126 ucrt) -- "How About a Twenty-Six" 4573
Click on any hostname to see more info about the system (e.g. compilers)      (*) as reported by 'uname -p', except on Windows and Mac OS X

Package 1484/2341HostnameOS / ArchINSTALLBUILDCHECKBUILD BIN
OmnipathR 3.16.0  (landing page)
Denes Turei
Snapshot Date: 2025-04-22 13:40 -0400 (Tue, 22 Apr 2025)
git_url: https://git.bioconductor.org/packages/OmnipathR
git_branch: RELEASE_3_21
git_last_commit: 08e98a0
git_last_commit_date: 2025-04-15 11:51:33 -0400 (Tue, 15 Apr 2025)
nebbiolo1Linux (Ubuntu 24.04.1 LTS) / x86_64  OK    OK    ERROR  
palomino7Windows Server 2022 Datacenter / x64  OK    OK    ERROR    OK  


CHECK results for OmnipathR on nebbiolo1

To the developers/maintainers of the OmnipathR package:
- Allow up to 24 hours (and sometimes 48 hours) for your latest push to git@git.bioconductor.org:packages/OmnipathR.git to reflect on this report. See Troubleshooting Build Report for more information.
- Use the following Renviron settings to reproduce errors and warnings.
- If 'R CMD check' started to fail recently on the Linux builder(s) over a missing dependency, add the missing dependency to 'Suggests:' in your DESCRIPTION file. See Renviron.bioc for more information.

raw results


Summary

Package: OmnipathR
Version: 3.16.0
Command: /home/biocbuild/bbs-3.21-bioc/R/bin/R CMD check --install=check:OmnipathR.install-out.txt --library=/home/biocbuild/bbs-3.21-bioc/R/site-library --timings OmnipathR_3.16.0.tar.gz
StartedAt: 2025-04-24 01:01:35 -0400 (Thu, 24 Apr 2025)
EndedAt: 2025-04-24 01:26:32 -0400 (Thu, 24 Apr 2025)
EllapsedTime: 1497.5 seconds
RetCode: 1
Status:   ERROR  
CheckDir: OmnipathR.Rcheck
Warnings: NA

Command output

##############################################################################
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###
### Running command:
###
###   /home/biocbuild/bbs-3.21-bioc/R/bin/R CMD check --install=check:OmnipathR.install-out.txt --library=/home/biocbuild/bbs-3.21-bioc/R/site-library --timings OmnipathR_3.16.0.tar.gz
###
##############################################################################
##############################################################################


* using log directory ‘/home/biocbuild/bbs-3.21-bioc/meat/OmnipathR.Rcheck’
* using R version 4.5.0 RC (2025-04-04 r88126)
* using platform: x86_64-pc-linux-gnu
* R was compiled by
    gcc (Ubuntu 13.3.0-6ubuntu2~24.04) 13.3.0
    GNU Fortran (Ubuntu 13.3.0-6ubuntu2~24.04) 13.3.0
* running under: Ubuntu 24.04.2 LTS
* using session charset: UTF-8
* checking for file ‘OmnipathR/DESCRIPTION’ ... OK
* checking extension type ... Package
* this is package ‘OmnipathR’ version ‘3.16.0’
* package encoding: UTF-8
* checking package namespace information ... OK
* checking package dependencies ... INFO
Imports includes 35 non-default packages.
Importing from so many packages makes the package vulnerable to any of
them becoming unavailable.  Move as many as possible to Suggests and
use conditionally.
* checking if this is a source package ... OK
* checking if there is a namespace ... OK
* checking for hidden files and directories ... OK
* checking for portable file names ... OK
* checking for sufficient/correct file permissions ... OK
* checking whether package ‘OmnipathR’ can be installed ... OK
* checking installed package size ... OK
* checking package directory ... OK
* checking DESCRIPTION meta-information ... OK
* checking top-level files ... OK
* checking for left-over files ... OK
* checking index information ... OK
* checking package subdirectories ... OK
* checking code files for non-ASCII characters ... OK
* checking R files for syntax errors ... OK
* checking whether the package can be loaded ... OK
* checking whether the package can be loaded with stated dependencies ... OK
* checking whether the package can be unloaded cleanly ... OK
* checking whether the namespace can be loaded with stated dependencies ... OK
* checking whether the namespace can be unloaded cleanly ... OK
* checking loading without being on the library search path ... OK
* checking whether startup messages can be suppressed ... NOTE
[2025-04-24 01:02:06] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:02:06] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:06] [INFO]    [OmnipathR] Initialized cache: `/home/biocbuild/.cache/OmnipathR`.
[2025-04-24 01:02:06] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-04-24 01:02:06] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-04-23
[2025-04-24 01:02:06] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.5.0; ; 2025-04-23 19:13:37 UTC; unix
[2025-04-24 01:02:06] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.16.0
[2025-04-24 01:02:06] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.21
[2025-04-24 01:02:07] [INFO]    [OmnipathR] Session info: [version=R version 4.5.0 RC (2025-04-04 r88126); os=Ubuntu 24.04.2 LTS; system=x86_64, linux-gnu; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-04-24; pandoc=2.7.3 @ /usr/bin/ (via rmarkdown); quarto=1.5.57 @ /usr/local/bin/quarto]
[2025-04-24 01:02:07] [INFO]    [OmnipathR] External libraries: [cairo=1.18.0; cairoFT=; pango=1.52.1; png=1.6.43; jpeg=8.0; tiff=LIBTIFF, Version 4.5.1; tcl=8.6.14; curl=8.5.0; zlib=1.3; bzlib=1.0.8, 13-Jul-2019; xz=5.4.5; deflate=1.19; PCRE=10.42 2022-12-11; ICU=74.2; TRE=TRE 0.8.0 R_fixes (BSD); iconv=glibc 2.39; readline=8.2; BLAS=/home/biocbuild/bbs-3.21-bioc/R/lib/libRblas.so; lapack=/usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0; lapack_version=3.12.0]
[2025-04-24 01:02:07] [INFO]    [OmnipathR] Loaded packages: backports 1.5.0(2024-05-23); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.2(2024-07-29); chromote 0.5.0(2025-03-21); cli 3.6.5(2025-04-23); crayon 1.5.3(2024-06-20); curl 6.2.2(2025-03-24); DBI 1.2.3(2024-06-02); digest 0.6.37(2024-08-19); dplyr 1.1.4(2023-11-17); evaluate 1.0.3(2025-01-10); fastmap 1.2.0(2024-05-15); fs 1.6.6(2025-04-12); generics 0.1.3(2022-07-05); glue 1.8.0(2024-09-30); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.1.2(2025-03-26); igraph 2.1.4(2025-01-23); jsonlite 2.0.0(2025-03-27); knitr 1.50(2025-03-16); later 1.4.2(2025-04-08); lifecycle 1.0.4(2023-11-07); logger 0.4.0(2024-10-22); lubridate 1.9.4(2024-12-08); magrittr 2.0.3(2022-03-30); memoise 2.0.1(2021-11-26); OmnipathR 3.16.0(2025-04-23); pillar 1.10.2(2025-04-05); pkgconfig 2.0.3(2019-09-22); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.2(2024-11-28); ps 1.9.1(2025-04-12); purrr 1.0.4(2025-02-05); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.0(2024-11-01); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.0.14(2025-01-12); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); RSQLite 2.3.9(2024-12-03); rvest 1.0.4(2024-02-12); sessioninfo 1.2.3(2025-02-05); stringi 1.8.7(2025-03-27); stringr 1.5.1(2023-11-14); tibble 3.2.1(2023-03-20); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.52(2025-04-02); XML 3.99-0.18(2025-01-01); xml2 1.3.8(2025-03-14); yaml 2.3.10(2024-07-26); zip 2.3.2(2025-02-01)
[2025-04-24 01:02:07] [INFO]    [OmnipathR] CURL: version: 8.5.0; headers: 8.5.0; ssl_version: OpenSSL/3.0.13; libz_version: 1.3; libssh_version: libssh/0.10.6/openssl/zlib; libidn_version: 2.3.7; host: x86_64-pc-linux-gnu; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtmp, rtmpe, rtmps, rtmpt, rtmpte, rtmpts, rtsp, scp, sftp, smb, smbs, smtp, smtps, telnet, tftp; ipv6: TRUE; http2: TRUE; idn: TRUE; url_parser: TRUE
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] Cache is at `/home/biocbuild/.cache/OmnipathR`.
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] Contains 1 files.
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:07] [SUCCESS] [OmnipathR] Removing all cache contents from `/home/biocbuild/.cache/OmnipathR`.
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] Pandoc version: `2.7.3`.
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:07] [TRACE]   [OmnipathR] Cache locked: FALSE

It looks like this package (or a package it requires) has a startup
message which cannot be suppressed: see ?packageStartupMessage.
* checking dependencies in R code ... OK
* checking S3 generic/method consistency ... OK
* checking replacement functions ... OK
* checking foreign function calls ... OK
* checking R code for possible problems ... NOTE
[2025-04-24 01:02:24] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:02:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:24] [INFO]    [OmnipathR] Initialized cache: `/home/biocbuild/.cache/OmnipathR`.
[2025-04-24 01:02:24] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-04-24 01:02:24] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-04-23
[2025-04-24 01:02:24] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.5.0; ; 2025-04-23 19:13:37 UTC; unix
[2025-04-24 01:02:24] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.16.0
[2025-04-24 01:02:24] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.21
[2025-04-24 01:02:24] [INFO]    [OmnipathR] Session info: [version=R version 4.5.0 RC (2025-04-04 r88126); os=Ubuntu 24.04.2 LTS; system=x86_64, linux-gnu; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-04-24; pandoc=2.7.3 @ /usr/bin/ (via rmarkdown); quarto=1.5.57 @ /usr/local/bin/quarto]
[2025-04-24 01:02:24] [INFO]    [OmnipathR] External libraries: [cairo=1.18.0; cairoFT=; pango=1.52.1; png=1.6.43; jpeg=8.0; tiff=LIBTIFF, Version 4.5.1; tcl=8.6.14; curl=8.5.0; zlib=1.3; bzlib=1.0.8, 13-Jul-2019; xz=5.4.5; deflate=1.19; PCRE=10.42 2022-12-11; ICU=74.2; TRE=TRE 0.8.0 R_fixes (BSD); iconv=glibc 2.39; readline=8.2; BLAS=/home/biocbuild/bbs-3.21-bioc/R/lib/libRblas.so; lapack=/usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0; lapack_version=3.12.0]
[2025-04-24 01:02:24] [INFO]    [OmnipathR] Loaded packages: backports 1.5.0(2024-05-23); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.2(2024-07-29); chromote 0.5.0(2025-03-21); cli 3.6.5(2025-04-23); crayon 1.5.3(2024-06-20); curl 6.2.2(2025-03-24); DBI 1.2.3(2024-06-02); digest 0.6.37(2024-08-19); dplyr 1.1.4(2023-11-17); evaluate 1.0.3(2025-01-10); fastmap 1.2.0(2024-05-15); fs 1.6.6(2025-04-12); generics 0.1.3(2022-07-05); glue 1.8.0(2024-09-30); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.1.2(2025-03-26); igraph 2.1.4(2025-01-23); jsonlite 2.0.0(2025-03-27); knitr 1.50(2025-03-16); later 1.4.2(2025-04-08); lifecycle 1.0.4(2023-11-07); logger 0.4.0(2024-10-22); lubridate 1.9.4(2024-12-08); magrittr 2.0.3(2022-03-30); memoise 2.0.1(2021-11-26); OmnipathR 3.16.0(2025-04-23); pillar 1.10.2(2025-04-05); pkgconfig 2.0.3(2019-09-22); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.2(2024-11-28); ps 1.9.1(2025-04-12); purrr 1.0.4(2025-02-05); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.0(2024-11-01); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.0.14(2025-01-12); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); RSQLite 2.3.9(2024-12-03); rvest 1.0.4(2024-02-12); sessioninfo 1.2.3(2025-02-05); stringi 1.8.7(2025-03-27); stringr 1.5.1(2023-11-14); tibble 3.2.1(2023-03-20); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.52(2025-04-02); XML 3.99-0.18(2025-01-01); xml2 1.3.8(2025-03-14); yaml 2.3.10(2024-07-26); zip 2.3.2(2025-02-01)
[2025-04-24 01:02:24] [INFO]    [OmnipathR] CURL: version: 8.5.0; headers: 8.5.0; ssl_version: OpenSSL/3.0.13; libz_version: 1.3; libssh_version: libssh/0.10.6/openssl/zlib; libidn_version: 2.3.7; host: x86_64-pc-linux-gnu; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtmp, rtmpe, rtmps, rtmpt, rtmpte, rtmpts, rtsp, scp, sftp, smb, smbs, smtp, smtps, telnet, tftp; ipv6: TRUE; http2: TRUE; idn: TRUE; url_parser: TRUE
[2025-04-24 01:02:24] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-04-24 01:02:24] [TRACE]   [OmnipathR] Cache is at `/home/biocbuild/.cache/OmnipathR`.
[2025-04-24 01:02:24] [TRACE]   [OmnipathR] Contains 1 files.
[2025-04-24 01:02:24] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-04-24 01:02:24] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:02:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:24] [SUCCESS] [OmnipathR] Removing all cache contents from `/home/biocbuild/.cache/OmnipathR`.
[2025-04-24 01:02:24] [TRACE]   [OmnipathR] Pandoc version: `2.7.3`.
[2025-04-24 01:02:25] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-04-24 01:02:25] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:25] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-04-24 01:02:25] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:25] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-04-24 01:02:25] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:25] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-04-24 01:02:25] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:02:25] [TRACE]   [OmnipathR] Cache locked: FALSE
* checking Rd files ... OK
* checking Rd metadata ... OK
* checking Rd cross-references ... OK
* checking for missing documentation entries ... OK
* checking for code/documentation mismatches ... OK
* checking Rd \usage sections ... OK
* checking Rd contents ... OK
* checking for unstated dependencies in examples ... OK
* checking R/sysdata.rda ... OK
* checking files in ‘vignettes’ ... OK
* checking examples ... ERROR
Running examples in ‘OmnipathR-Ex.R’ failed
The error most likely occurred in:

> base::assign(".ptime", proc.time(), pos = "CheckExEnv")
> ### Name: curated_ligrec_stats
> ### Title: Statistics about literature curated ligand-receptor interactions
> ### Aliases: curated_ligrec_stats
> 
> ### ** Examples
> 
> clr <- curated_ligrec_stats()
Warning in import_post_translational_interactions(resources = ., ...) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:37] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:37] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=[Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020],query_type=interactions]
[2025-04-24 01:05:37] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:37] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:37] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:37] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:37] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:37] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/69503cb1a01671e7c77c0e80e6ca0ce4110a89fe-1.rds`.
[2025-04-24 01:05:37] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:38] [SUCCESS] [OmnipathR] Loaded 4568 interactions from cache.
Warning in (function (...)  : 'function (...) 
{
    .Deprecated("post_translational")
    post_translational(...)
}' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:38] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:38] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellPhoneDB,fields=extra_attrs,query_type=interactions]
[2025-04-24 01:05:38] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:38] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:38] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:38] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:38] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:38] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/ec8c89037e2c920468342c7c2326c74a5474eedc-1.rds`.
[2025-04-24 01:05:38] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:38] [TRACE]   [OmnipathR] Converting JSON column `extra_attrs` to list.
[2025-04-24 01:05:39] [SUCCESS] [OmnipathR] Loaded 2879 interactions from cache.
Warning in (function (...)  : 'function (...) 
{
    .Deprecated("post_translational")
    post_translational(...)
}' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:39] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:39] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Cellinker,fields=extra_attrs,query_type=interactions]
[2025-04-24 01:05:39] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:39] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:40] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:40] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:40] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:40] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/8173bc9dfc09711dc80f48d9c3c5bd57af3d8be5-1.rds`.
[2025-04-24 01:05:40] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:40] [TRACE]   [OmnipathR] Converting JSON column `extra_attrs` to list.
[2025-04-24 01:05:40] [SUCCESS] [OmnipathR] Loaded 3765 interactions from cache.
Warning in (function (...)  : 'function (...) 
{
    .Deprecated("post_translational")
    post_translational(...)
}' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:40] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:40] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=talklr,fields=extra_attrs,query_type=interactions]
[2025-04-24 01:05:40] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:40] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:41] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:41] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:41] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:41] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/b2de51666493a9c70a7b375972a2557903c14763-1.rds`.
[2025-04-24 01:05:41] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:41] [TRACE]   [OmnipathR] Converting JSON column `extra_attrs` to list.
[2025-04-24 01:05:42] [SUCCESS] [OmnipathR] Loaded 2484 interactions from cache.
Warning in (function (...)  : 'function (...) 
{
    .Deprecated("post_translational")
    post_translational(...)
}' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:42] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:42] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellChatDB,fields=extra_attrs,query_type=interactions]
[2025-04-24 01:05:42] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:42] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:43] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:43] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:43] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:43] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/fedf7fd37a8e863f804aa073f2ae480ff78001e5-1.rds`.
[2025-04-24 01:05:43] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:43] [TRACE]   [OmnipathR] Converting JSON column `extra_attrs` to list.
[2025-04-24 01:05:43] [SUCCESS] [OmnipathR] Loaded 1894 interactions from cache.
[2025-04-24 01:05:43] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:43] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=SignaLink3,query_type=interactions]
[2025-04-24 01:05:43] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:43] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:44] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:44] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:44] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=SignaLink3&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:44] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/95ee739b50bbfea2c48e5c86a64525084a1dab30-1.rds`.
[2025-04-24 01:05:44] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=SignaLink3&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:44] [SUCCESS] [OmnipathR] Loaded 1796 interactions from cache.
[2025-04-24 01:05:44] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:44] [TRACE]   [OmnipathR] Arguments for OmniPath query: [wide=FALSE,resources=SignaLink_function,query_type=annotations]
[2025-04-24 01:05:44] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:44] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:45] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:45] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:45] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/annotations?resources=SignaLink_function&license=academic`
[2025-04-24 01:05:45] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/4190db12b9aabca9c0851ec84aa3fbb71b5dfbcd-1.rds`.
[2025-04-24 01:05:45] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/annotations?resources=SignaLink_function&license=academic`
[2025-04-24 01:05:45] [SUCCESS] [OmnipathR] Loaded 2001 annotation records from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:45] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:45] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellPhoneDB,query_type=interactions]
[2025-04-24 01:05:45] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:45] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:46] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:46] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:46] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.327778s from omnipathdb.org (47.8 Kb/s); Redirect: 0s, DNS look up: 0.00158s, Connection: 0.002591s, Pretransfer: 0.16482s, First byte at: 0.326846s
[2025-04-24 01:05:46] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:05:46 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:05:46 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:05:47] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:47] [INFO]    [OmnipathR] Cache item `afe18d85fba82fa7d5f390113de328e13aa85e89` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/afe18d85fba82fa7d5f390113de328e13aa85e89-1.rds`.
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/afe18d85fba82fa7d5f390113de328e13aa85e89-1.rds`.
[2025-04-24 01:05:47] [INFO]    [OmnipathR] Download ready [key=afe18d85fba82fa7d5f390113de328e13aa85e89, version=1]
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:47] [INFO]    [OmnipathR] Cache item `afe18d85fba82fa7d5f390113de328e13aa85e89` version 1: status changed from `started` to `ready`.
[2025-04-24 01:05:47] [SUCCESS] [OmnipathR] Downloaded 2879 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellPhoneDB,query_type=interactions]
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:47] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:48] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:48] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:48] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:48] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/afe18d85fba82fa7d5f390113de328e13aa85e89-1.rds`.
[2025-04-24 01:05:48] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:48] [SUCCESS] [OmnipathR] Loaded 2879 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:48] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:48] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellPhoneDB,query_type=interactions]
[2025-04-24 01:05:48] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:49] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:49] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:49] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:49] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:49] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/afe18d85fba82fa7d5f390113de328e13aa85e89-1.rds`.
[2025-04-24 01:05:49] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:50] [SUCCESS] [OmnipathR] Loaded 2879 interactions from cache.
Warning in (function (...)  : 'function (...) 
{
    .Deprecated("post_translational")
    post_translational(...)
}' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:50] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:50] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellPhoneDB,fields=extra_attrs,query_type=interactions]
[2025-04-24 01:05:50] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:50] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:50] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:50] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:51] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:51] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/ec8c89037e2c920468342c7c2326c74a5474eedc-1.rds`.
[2025-04-24 01:05:51] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:51] [TRACE]   [OmnipathR] Converting JSON column `extra_attrs` to list.
[2025-04-24 01:05:51] [SUCCESS] [OmnipathR] Loaded 2879 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:51] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:51] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Cellinker,query_type=interactions]
[2025-04-24 01:05:51] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:51] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:52] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:52] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:52] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.317793s from omnipathdb.org (49.3 Kb/s); Redirect: 0s, DNS look up: 0.001442s, Connection: 0.002458s, Pretransfer: 0.15931s, First byte at: 0.317358s
[2025-04-24 01:05:52] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:05:52 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:05:52 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:05:53] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:53] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:05:53] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:53] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:05:53] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:53] [INFO]    [OmnipathR] Cache item `c8350370602bcfe8ed14bda96cb9bd68770c1e66` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:05:53] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/c8350370602bcfe8ed14bda96cb9bd68770c1e66-1.rds`.
[2025-04-24 01:05:53] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/c8350370602bcfe8ed14bda96cb9bd68770c1e66-1.rds`.
[2025-04-24 01:05:53] [INFO]    [OmnipathR] Download ready [key=c8350370602bcfe8ed14bda96cb9bd68770c1e66, version=1]
[2025-04-24 01:05:53] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:05:53] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:53] [INFO]    [OmnipathR] Cache item `c8350370602bcfe8ed14bda96cb9bd68770c1e66` version 1: status changed from `started` to `ready`.
[2025-04-24 01:05:54] [SUCCESS] [OmnipathR] Downloaded 3765 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:54] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:54] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Cellinker,query_type=interactions]
[2025-04-24 01:05:54] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:54] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:54] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:54] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:55] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:55] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/c8350370602bcfe8ed14bda96cb9bd68770c1e66-1.rds`.
[2025-04-24 01:05:55] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:55] [SUCCESS] [OmnipathR] Loaded 3765 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:55] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:55] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Cellinker,query_type=interactions]
[2025-04-24 01:05:55] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:55] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:55] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:55] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:56] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:56] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/c8350370602bcfe8ed14bda96cb9bd68770c1e66-1.rds`.
[2025-04-24 01:05:56] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:56] [SUCCESS] [OmnipathR] Loaded 3765 interactions from cache.
Warning in (function (...)  : 'function (...) 
{
    .Deprecated("post_translational")
    post_translational(...)
}' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:56] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:56] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Cellinker,fields=extra_attrs,query_type=interactions]
[2025-04-24 01:05:56] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:56] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:56] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:56] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:57] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:57] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/8173bc9dfc09711dc80f48d9c3c5bd57af3d8be5-1.rds`.
[2025-04-24 01:05:57] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:05:57] [TRACE]   [OmnipathR] Converting JSON column `extra_attrs` to list.
[2025-04-24 01:05:57] [SUCCESS] [OmnipathR] Loaded 3765 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:05:57] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:05:57] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellTalkDB,query_type=interactions]
[2025-04-24 01:05:57] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:05:57] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:58] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:58] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:58] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.334855s from omnipathdb.org (46.8 Kb/s); Redirect: 0s, DNS look up: 0.00164s, Connection: 0.00249s, Pretransfer: 0.162421s, First byte at: 0.33442s
[2025-04-24 01:05:58] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:05:58 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:05:58 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:05:59] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:05:59] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:05:59] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:59] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:05:59] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:05:59] [INFO]    [OmnipathR] Cache item `8158e608d1fd5182b9aa0a24a07fc739c59a1bf8` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:05:59] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/8158e608d1fd5182b9aa0a24a07fc739c59a1bf8-1.rds`.
[2025-04-24 01:06:00] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/8158e608d1fd5182b9aa0a24a07fc739c59a1bf8-1.rds`.
[2025-04-24 01:06:00] [INFO]    [OmnipathR] Download ready [key=8158e608d1fd5182b9aa0a24a07fc739c59a1bf8, version=1]
[2025-04-24 01:06:00] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:00] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:00] [INFO]    [OmnipathR] Cache item `8158e608d1fd5182b9aa0a24a07fc739c59a1bf8` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:00] [SUCCESS] [OmnipathR] Downloaded 3473 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:00] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:00] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellTalkDB,query_type=interactions]
[2025-04-24 01:06:00] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:00] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:00] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:00] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:01] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:01] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/8158e608d1fd5182b9aa0a24a07fc739c59a1bf8-1.rds`.
[2025-04-24 01:06:01] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:01] [SUCCESS] [OmnipathR] Loaded 3473 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:01] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:01] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellTalkDB,query_type=interactions]
[2025-04-24 01:06:01] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:01] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:02] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:02] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:02] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:02] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/8158e608d1fd5182b9aa0a24a07fc739c59a1bf8-1.rds`.
[2025-04-24 01:06:02] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:02] [SUCCESS] [OmnipathR] Loaded 3473 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:02] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:02] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellTalkDB,query_type=interactions]
[2025-04-24 01:06:02] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:02] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:03] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:03] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:03] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:03] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/8158e608d1fd5182b9aa0a24a07fc739c59a1bf8-1.rds`.
[2025-04-24 01:06:03] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellTalkDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:03] [SUCCESS] [OmnipathR] Loaded 3473 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:03] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:03] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellChatDB,query_type=interactions]
[2025-04-24 01:06:03] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:03] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:04] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:04] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:04] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:04] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:04] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:04] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:04] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:04] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:04] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:04] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:06:04] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:06:04] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:06:04] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:06:05] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.331214s from omnipathdb.org (47.3 Kb/s); Redirect: 0s, DNS look up: 0.001847s, Connection: 0.002686s, Pretransfer: 0.165183s, First byte at: 0.330088s
[2025-04-24 01:06:05] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:06:04 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:06:04 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:06:05] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:05] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:05] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:05] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:05] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:05] [INFO]    [OmnipathR] Cache item `641434253ee9e555515168e62fe5c7e36a8596c6` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:06:05] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/641434253ee9e555515168e62fe5c7e36a8596c6-1.rds`.
[2025-04-24 01:06:05] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/641434253ee9e555515168e62fe5c7e36a8596c6-1.rds`.
[2025-04-24 01:06:05] [INFO]    [OmnipathR] Download ready [key=641434253ee9e555515168e62fe5c7e36a8596c6, version=1]
[2025-04-24 01:06:05] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:05] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:06] [INFO]    [OmnipathR] Cache item `641434253ee9e555515168e62fe5c7e36a8596c6` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:06] [SUCCESS] [OmnipathR] Downloaded 1894 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:06] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:06] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellChatDB,query_type=interactions]
[2025-04-24 01:06:06] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:06] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:06] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:06] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:06] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:06] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/641434253ee9e555515168e62fe5c7e36a8596c6-1.rds`.
[2025-04-24 01:06:06] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:07] [SUCCESS] [OmnipathR] Loaded 1894 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:07] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:07] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellChatDB,query_type=interactions]
[2025-04-24 01:06:07] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:07] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:07] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:07] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:07] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:07] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/641434253ee9e555515168e62fe5c7e36a8596c6-1.rds`.
[2025-04-24 01:06:07] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:08] [SUCCESS] [OmnipathR] Loaded 1894 interactions from cache.
Warning in (function (...)  : 'function (...) 
{
    .Deprecated("post_translational")
    post_translational(...)
}' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:08] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:08] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellChatDB,fields=extra_attrs,query_type=interactions]
[2025-04-24 01:06:08] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:08] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:08] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:08] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:08] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:06:08] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/fedf7fd37a8e863f804aa073f2ae480ff78001e5-1.rds`.
[2025-04-24 01:06:08] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:06:08] [TRACE]   [OmnipathR] Converting JSON column `extra_attrs` to list.
[2025-04-24 01:06:09] [SUCCESS] [OmnipathR] Loaded 1894 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:09] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:09] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellCall,query_type=interactions]
[2025-04-24 01:06:09] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:09] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:09] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:09] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:10] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:10] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:10] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:10] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:10] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:10] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:10] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:10] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:06:10] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:06:10] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:06:10] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:06:10] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.352973s from omnipathdb.org (44.4 Kb/s); Redirect: 0s, DNS look up: 0.001545s, Connection: 0.002208s, Pretransfer: 0.169113s, First byte at: 0.352052s
[2025-04-24 01:06:10] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:06:10 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:06:10 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:06:11] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:11] [INFO]    [OmnipathR] Cache item `af0debe0cdd22707b097cd388dfd1398cccb76c8` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/af0debe0cdd22707b097cd388dfd1398cccb76c8-1.rds`.
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/af0debe0cdd22707b097cd388dfd1398cccb76c8-1.rds`.
[2025-04-24 01:06:11] [INFO]    [OmnipathR] Download ready [key=af0debe0cdd22707b097cd388dfd1398cccb76c8, version=1]
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:11] [INFO]    [OmnipathR] Cache item `af0debe0cdd22707b097cd388dfd1398cccb76c8` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:11] [SUCCESS] [OmnipathR] Downloaded 1000 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellCall,query_type=interactions]
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:11] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:12] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:12] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:12] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:12] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/af0debe0cdd22707b097cd388dfd1398cccb76c8-1.rds`.
[2025-04-24 01:06:12] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:12] [SUCCESS] [OmnipathR] Loaded 1000 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:12] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:12] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellCall,query_type=interactions]
[2025-04-24 01:06:12] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:12] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:12] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:12] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:13] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:13] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/af0debe0cdd22707b097cd388dfd1398cccb76c8-1.rds`.
[2025-04-24 01:06:13] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:13] [SUCCESS] [OmnipathR] Loaded 1000 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:13] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:13] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=CellCall,query_type=interactions]
[2025-04-24 01:06:13] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:13] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:13] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:13] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:13] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/af0debe0cdd22707b097cd388dfd1398cccb76c8-1.rds`.
[2025-04-24 01:06:13] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellCall&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:14] [SUCCESS] [OmnipathR] Loaded 1000 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=connectomeDB2020,query_type=interactions]
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:14] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:14] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:14] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:06:14] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:06:15] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:06:15] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.33604s from omnipathdb.org (46.6 Kb/s); Redirect: 0s, DNS look up: 0.001467s, Connection: 0.002203s, Pretransfer: 0.178765s, First byte at: 0.335503s
[2025-04-24 01:06:15] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:06:15 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:06:15 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:06:16] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:16] [INFO]    [OmnipathR] Cache item `d08eb76734c005daabb6eb3c832a55e330672026` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/d08eb76734c005daabb6eb3c832a55e330672026-1.rds`.
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/d08eb76734c005daabb6eb3c832a55e330672026-1.rds`.
[2025-04-24 01:06:16] [INFO]    [OmnipathR] Download ready [key=d08eb76734c005daabb6eb3c832a55e330672026, version=1]
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:16] [INFO]    [OmnipathR] Cache item `d08eb76734c005daabb6eb3c832a55e330672026` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:16] [SUCCESS] [OmnipathR] Downloaded 2313 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=connectomeDB2020,query_type=interactions]
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:16] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:17] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:17] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:17] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:17] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/d08eb76734c005daabb6eb3c832a55e330672026-1.rds`.
[2025-04-24 01:06:17] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:17] [SUCCESS] [OmnipathR] Loaded 2313 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:17] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:17] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=connectomeDB2020,query_type=interactions]
[2025-04-24 01:06:17] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:17] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:18] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:18] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:18] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:18] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/d08eb76734c005daabb6eb3c832a55e330672026-1.rds`.
[2025-04-24 01:06:18] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:18] [SUCCESS] [OmnipathR] Loaded 2313 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:18] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:18] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=connectomeDB2020,query_type=interactions]
[2025-04-24 01:06:18] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:18] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:19] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:19] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:19] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/d08eb76734c005daabb6eb3c832a55e330672026-1.rds`.
[2025-04-24 01:06:19] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:19] [SUCCESS] [OmnipathR] Loaded 2313 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:19] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:19] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Guide2Pharma,query_type=interactions]
[2025-04-24 01:06:19] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:19] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:20] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:20] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:20] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:20] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:20] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:20] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:20] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:20] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:20] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:20] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:06:20] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:06:20] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:06:21] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:06:21] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.316594s from omnipathdb.org (49.5 Kb/s); Redirect: 0s, DNS look up: 0.001646s, Connection: 0.002382s, Pretransfer: 0.158181s, First byte at: 0.316176s
[2025-04-24 01:06:21] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:06:21 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:06:21 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:06:21] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:21] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:21] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:21] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:21] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:21] [INFO]    [OmnipathR] Cache item `11b0dd49c2e8541d966f577a8aacd52c71112987` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:06:21] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/11b0dd49c2e8541d966f577a8aacd52c71112987-1.rds`.
[2025-04-24 01:06:21] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/11b0dd49c2e8541d966f577a8aacd52c71112987-1.rds`.
[2025-04-24 01:06:21] [INFO]    [OmnipathR] Download ready [key=11b0dd49c2e8541d966f577a8aacd52c71112987, version=1]
[2025-04-24 01:06:21] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:21] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:21] [INFO]    [OmnipathR] Cache item `11b0dd49c2e8541d966f577a8aacd52c71112987` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:22] [SUCCESS] [OmnipathR] Downloaded 672 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Guide2Pharma,query_type=interactions]
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/11b0dd49c2e8541d966f577a8aacd52c71112987-1.rds`.
[2025-04-24 01:06:22] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:22] [SUCCESS] [OmnipathR] Loaded 672 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Guide2Pharma,query_type=interactions]
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:22] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:23] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:23] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:23] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:23] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/11b0dd49c2e8541d966f577a8aacd52c71112987-1.rds`.
[2025-04-24 01:06:23] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:23] [SUCCESS] [OmnipathR] Loaded 672 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:23] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:23] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Guide2Pharma,query_type=interactions]
[2025-04-24 01:06:23] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:23] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:24] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:24] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:24] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/11b0dd49c2e8541d966f577a8aacd52c71112987-1.rds`.
[2025-04-24 01:06:24] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:24] [SUCCESS] [OmnipathR] Loaded 672 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:24] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:24] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Baccin2019,query_type=interactions]
[2025-04-24 01:06:24] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:24] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:25] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:25] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:25] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:25] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:25] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:25] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:25] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:25] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:25] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:25] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:06:25] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:06:25] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:06:26] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:06:26] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.34778s from omnipathdb.org (45 Kb/s); Redirect: 0s, DNS look up: 0.001845s, Connection: 0.002433s, Pretransfer: 0.191128s, First byte at: 0.346837s
[2025-04-24 01:06:26] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:06:25 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:06:25 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:06:26] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:26] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:26] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:27] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:27] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:27] [INFO]    [OmnipathR] Cache item `f963006a054fdbb2fcbd5a63e731087e21fb4b31` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:06:27] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/f963006a054fdbb2fcbd5a63e731087e21fb4b31-1.rds`.
[2025-04-24 01:06:27] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/f963006a054fdbb2fcbd5a63e731087e21fb4b31-1.rds`.
[2025-04-24 01:06:27] [INFO]    [OmnipathR] Download ready [key=f963006a054fdbb2fcbd5a63e731087e21fb4b31, version=1]
[2025-04-24 01:06:27] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:27] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:27] [INFO]    [OmnipathR] Cache item `f963006a054fdbb2fcbd5a63e731087e21fb4b31` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:27] [SUCCESS] [OmnipathR] Downloaded 1676 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:27] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:27] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Baccin2019,query_type=interactions]
[2025-04-24 01:06:27] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:27] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:28] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:28] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:28] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:28] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/f963006a054fdbb2fcbd5a63e731087e21fb4b31-1.rds`.
[2025-04-24 01:06:28] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:28] [SUCCESS] [OmnipathR] Loaded 1676 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:28] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:28] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Baccin2019,query_type=interactions]
[2025-04-24 01:06:28] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:28] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:29] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:29] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:29] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:29] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/f963006a054fdbb2fcbd5a63e731087e21fb4b31-1.rds`.
[2025-04-24 01:06:29] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:29] [SUCCESS] [OmnipathR] Loaded 1676 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:29] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:29] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Baccin2019,query_type=interactions]
[2025-04-24 01:06:29] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:29] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:30] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:30] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:30] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:30] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/f963006a054fdbb2fcbd5a63e731087e21fb4b31-1.rds`.
[2025-04-24 01:06:30] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Baccin2019&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:30] [SUCCESS] [OmnipathR] Loaded 1676 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:30] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:30] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Kirouac2010,query_type=interactions]
[2025-04-24 01:06:30] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:30] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:31] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:31] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:31] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.314994s from omnipathdb.org (49.7 Kb/s); Redirect: 0s, DNS look up: 0.001389s, Connection: 0.002137s, Pretransfer: 0.158792s, First byte at: 0.313994s
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:06:31 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:06:31 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:06:31] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:31] [INFO]    [OmnipathR] Cache item `e59c495f650b38ab64da89e0da5af6ff096901b8` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/e59c495f650b38ab64da89e0da5af6ff096901b8-1.rds`.
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/e59c495f650b38ab64da89e0da5af6ff096901b8-1.rds`.
[2025-04-24 01:06:31] [INFO]    [OmnipathR] Download ready [key=e59c495f650b38ab64da89e0da5af6ff096901b8, version=1]
[2025-04-24 01:06:31] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:32] [INFO]    [OmnipathR] Cache item `e59c495f650b38ab64da89e0da5af6ff096901b8` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:32] [SUCCESS] [OmnipathR] Downloaded 152 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Kirouac2010,query_type=interactions]
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/e59c495f650b38ab64da89e0da5af6ff096901b8-1.rds`.
[2025-04-24 01:06:32] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:32] [SUCCESS] [OmnipathR] Loaded 152 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Kirouac2010,query_type=interactions]
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:32] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:33] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:33] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:33] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:33] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/e59c495f650b38ab64da89e0da5af6ff096901b8-1.rds`.
[2025-04-24 01:06:33] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:33] [SUCCESS] [OmnipathR] Loaded 152 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:33] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:33] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Kirouac2010,query_type=interactions]
[2025-04-24 01:06:33] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:33] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:34] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:34] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:34] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:34] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/e59c495f650b38ab64da89e0da5af6ff096901b8-1.rds`.
[2025-04-24 01:06:34] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Kirouac2010&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:34] [SUCCESS] [OmnipathR] Loaded 152 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:34] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:34] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Ramilowski2015,query_type=interactions]
[2025-04-24 01:06:34] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:34] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:35] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:35] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:35] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:35] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:35] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:35] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:35] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:35] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:35] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:35] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:06:35] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:06:35] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:06:35] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:06:35] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.326324s from omnipathdb.org (48 Kb/s); Redirect: 0s, DNS look up: 0.00182s, Connection: 0.002487s, Pretransfer: 0.1634s, First byte at: 0.325457s
[2025-04-24 01:06:36] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:06:35 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:06:35 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:06:36] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:36] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:36] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:36] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:37] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:37] [INFO]    [OmnipathR] Cache item `78bff68f8413d6211070111914db1b8b2b98ad54` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:06:37] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/78bff68f8413d6211070111914db1b8b2b98ad54-1.rds`.
[2025-04-24 01:06:37] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/78bff68f8413d6211070111914db1b8b2b98ad54-1.rds`.
[2025-04-24 01:06:37] [INFO]    [OmnipathR] Download ready [key=78bff68f8413d6211070111914db1b8b2b98ad54, version=1]
[2025-04-24 01:06:37] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:37] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:37] [INFO]    [OmnipathR] Cache item `78bff68f8413d6211070111914db1b8b2b98ad54` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:37] [SUCCESS] [OmnipathR] Downloaded 1946 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:37] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:37] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Ramilowski2015,query_type=interactions]
[2025-04-24 01:06:37] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:37] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:38] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:38] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:38] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:38] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/78bff68f8413d6211070111914db1b8b2b98ad54-1.rds`.
[2025-04-24 01:06:38] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:38] [SUCCESS] [OmnipathR] Loaded 1946 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:38] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:38] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Ramilowski2015,query_type=interactions]
[2025-04-24 01:06:38] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:38] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:39] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:39] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:39] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:39] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/78bff68f8413d6211070111914db1b8b2b98ad54-1.rds`.
[2025-04-24 01:06:39] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:39] [SUCCESS] [OmnipathR] Loaded 1946 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:39] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:39] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=Ramilowski2015,query_type=interactions]
[2025-04-24 01:06:39] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:39] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:40] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:40] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:40] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:40] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/78bff68f8413d6211070111914db1b8b2b98ad54-1.rds`.
[2025-04-24 01:06:40] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Ramilowski2015&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:40] [SUCCESS] [OmnipathR] Loaded 1946 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:40] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:40] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=scConnect,query_type=interactions]
[2025-04-24 01:06:40] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:40] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:41] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:41] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:41] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.32862s from omnipathdb.org (47.7 Kb/s); Redirect: 0s, DNS look up: 0.001769s, Connection: 0.002603s, Pretransfer: 0.164375s, First byte at: 0.327722s
[2025-04-24 01:06:41] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:06:41 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:06:41 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:06:42] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:42] [INFO]    [OmnipathR] Cache item `4d3e24d35f89a47701b9f0e9d5da90ec2aee0874` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/4d3e24d35f89a47701b9f0e9d5da90ec2aee0874-1.rds`.
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/4d3e24d35f89a47701b9f0e9d5da90ec2aee0874-1.rds`.
[2025-04-24 01:06:42] [INFO]    [OmnipathR] Download ready [key=4d3e24d35f89a47701b9f0e9d5da90ec2aee0874, version=1]
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:42] [INFO]    [OmnipathR] Cache item `4d3e24d35f89a47701b9f0e9d5da90ec2aee0874` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:42] [SUCCESS] [OmnipathR] Downloaded 479 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=scConnect,query_type=interactions]
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:42] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/4d3e24d35f89a47701b9f0e9d5da90ec2aee0874-1.rds`.
[2025-04-24 01:06:43] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:43] [SUCCESS] [OmnipathR] Loaded 479 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=scConnect,query_type=interactions]
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:43] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/4d3e24d35f89a47701b9f0e9d5da90ec2aee0874-1.rds`.
[2025-04-24 01:06:43] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:44] [SUCCESS] [OmnipathR] Loaded 479 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=scConnect,query_type=interactions]
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/4d3e24d35f89a47701b9f0e9d5da90ec2aee0874-1.rds`.
[2025-04-24 01:06:44] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=scConnect&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:44] [SUCCESS] [OmnipathR] Loaded 479 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=talklr,query_type=interactions]
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:44] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:45] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:45] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:45] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:45] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:45] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:45] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:45] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:45] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:45] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:45] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:06:45] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:06:45] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:06:46] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:06:46] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.297764s from omnipathdb.org (52.6 Kb/s); Redirect: 0s, DNS look up: 0.001429s, Connection: 0.00198s, Pretransfer: 0.148467s, First byte at: 0.297314s
[2025-04-24 01:06:46] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:06:45 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:06:45 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:06:46] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:46] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:46] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:47] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:47] [INFO]    [OmnipathR] Cache item `2fed349a0caf2a5e7555cbd27caa66d55fd06302` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:06:47] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/2fed349a0caf2a5e7555cbd27caa66d55fd06302-1.rds`.
[2025-04-24 01:06:47] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/2fed349a0caf2a5e7555cbd27caa66d55fd06302-1.rds`.
[2025-04-24 01:06:47] [INFO]    [OmnipathR] Download ready [key=2fed349a0caf2a5e7555cbd27caa66d55fd06302, version=1]
[2025-04-24 01:06:47] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:47] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:47] [INFO]    [OmnipathR] Cache item `2fed349a0caf2a5e7555cbd27caa66d55fd06302` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:47] [SUCCESS] [OmnipathR] Downloaded 2484 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:47] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:47] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=talklr,query_type=interactions]
[2025-04-24 01:06:47] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:47] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:48] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:48] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:48] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:48] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/2fed349a0caf2a5e7555cbd27caa66d55fd06302-1.rds`.
[2025-04-24 01:06:48] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:48] [SUCCESS] [OmnipathR] Loaded 2484 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:48] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:48] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=talklr,query_type=interactions]
[2025-04-24 01:06:48] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:48] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:49] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:49] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:49] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:49] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/2fed349a0caf2a5e7555cbd27caa66d55fd06302-1.rds`.
[2025-04-24 01:06:49] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:49] [SUCCESS] [OmnipathR] Loaded 2484 interactions from cache.
Warning in (function (...)  : 'function (...) 
{
    .Deprecated("post_translational")
    post_translational(...)
}' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:49] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:49] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=talklr,fields=extra_attrs,query_type=interactions]
[2025-04-24 01:06:49] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:49] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:50] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:50] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:50] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:06:50] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/b2de51666493a9c70a7b375972a2557903c14763-1.rds`.
[2025-04-24 01:06:50] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic`
[2025-04-24 01:06:50] [TRACE]   [OmnipathR] Converting JSON column `extra_attrs` to list.
[2025-04-24 01:06:50] [SUCCESS] [OmnipathR] Loaded 2484 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:51] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:51] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=ICELLNET,query_type=interactions]
[2025-04-24 01:06:51] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:51] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:51] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:51] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:51] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:51] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:51] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:51] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:51] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:51] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:52] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:52] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:06:52] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:06:52] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:06:52] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:06:52] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.340496s from omnipathdb.org (46 Kb/s); Redirect: 0s, DNS look up: 0.001762s, Connection: 0.00233s, Pretransfer: 0.169809s, First byte at: 0.339652s
[2025-04-24 01:06:52] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:06:52 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:06:52 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:06:52] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:52] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:52] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:53] [INFO]    [OmnipathR] Cache item `d78f1e5d23782453249e01fb0379efde9c053131` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/d78f1e5d23782453249e01fb0379efde9c053131-1.rds`.
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/d78f1e5d23782453249e01fb0379efde9c053131-1.rds`.
[2025-04-24 01:06:53] [INFO]    [OmnipathR] Download ready [key=d78f1e5d23782453249e01fb0379efde9c053131, version=1]
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:53] [INFO]    [OmnipathR] Cache item `d78f1e5d23782453249e01fb0379efde9c053131` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:53] [SUCCESS] [OmnipathR] Downloaded 1018 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=ICELLNET,query_type=interactions]
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:53] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:54] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:54] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/d78f1e5d23782453249e01fb0379efde9c053131-1.rds`.
[2025-04-24 01:06:54] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:54] [SUCCESS] [OmnipathR] Loaded 1018 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:54] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:54] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=ICELLNET,query_type=interactions]
[2025-04-24 01:06:54] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:54] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:54] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:54] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:54] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:54] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/d78f1e5d23782453249e01fb0379efde9c053131-1.rds`.
[2025-04-24 01:06:54] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:55] [SUCCESS] [OmnipathR] Loaded 1018 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:55] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:55] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=ICELLNET,query_type=interactions]
[2025-04-24 01:06:55] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:55] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:55] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:55] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:55] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:55] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/d78f1e5d23782453249e01fb0379efde9c053131-1.rds`.
[2025-04-24 01:06:55] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=ICELLNET&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:55] [SUCCESS] [OmnipathR] Loaded 1018 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=EMBRACE,query_type=interactions]
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:56] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:56] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:56] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:06:56] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:06:57] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:06:57] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.317145s from omnipathdb.org (49.4 Kb/s); Redirect: 0s, DNS look up: 0.001477s, Connection: 0.002207s, Pretransfer: 0.157952s, First byte at: 0.316235s
[2025-04-24 01:06:57] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:06:56 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:06:56 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:06:57] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:57] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:57] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:57] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:57] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:57] [INFO]    [OmnipathR] Cache item `ef7eb533b45a8e6a8f4b6e928698c193d947a86b` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:06:57] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/ef7eb533b45a8e6a8f4b6e928698c193d947a86b-1.rds`.
[2025-04-24 01:06:57] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/ef7eb533b45a8e6a8f4b6e928698c193d947a86b-1.rds`.
[2025-04-24 01:06:57] [INFO]    [OmnipathR] Download ready [key=ef7eb533b45a8e6a8f4b6e928698c193d947a86b, version=1]
[2025-04-24 01:06:57] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:06:58] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:58] [INFO]    [OmnipathR] Cache item `ef7eb533b45a8e6a8f4b6e928698c193d947a86b` version 1: status changed from `started` to `ready`.
[2025-04-24 01:06:58] [SUCCESS] [OmnipathR] Downloaded 1707 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:58] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:58] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=EMBRACE,query_type=interactions]
[2025-04-24 01:06:58] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:58] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:58] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:58] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:58] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:58] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/ef7eb533b45a8e6a8f4b6e928698c193d947a86b-1.rds`.
[2025-04-24 01:06:58] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:59] [SUCCESS] [OmnipathR] Loaded 1707 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:06:59] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:06:59] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=EMBRACE,query_type=interactions]
[2025-04-24 01:06:59] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:06:59] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:06:59] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:06:59] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:06:59] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:06:59] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/ef7eb533b45a8e6a8f4b6e928698c193d947a86b-1.rds`.
[2025-04-24 01:06:59] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:00] [SUCCESS] [OmnipathR] Loaded 1707 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:07:00] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:07:00] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=EMBRACE,query_type=interactions]
[2025-04-24 01:07:00] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:07:00] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:07:00] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:07:00] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:00] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:00] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/ef7eb533b45a8e6a8f4b6e928698c193d947a86b-1.rds`.
[2025-04-24 01:07:00] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=EMBRACE&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:00] [SUCCESS] [OmnipathR] Loaded 1707 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=LRdb,query_type=interactions]
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:01] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:01] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:01] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:07:01] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:07:02] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:07:02] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.330998s from omnipathdb.org (47.3 Kb/s); Redirect: 0s, DNS look up: 0.001352s, Connection: 0.002109s, Pretransfer: 0.165658s, First byte at: 0.330601s
[2025-04-24 01:07:02] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:07:02 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:07:02 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:07:03] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:03] [INFO]    [OmnipathR] Cache item `0ae240e6276d9da6cd5c362b0e477962ece2e997` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/0ae240e6276d9da6cd5c362b0e477962ece2e997-1.rds`.
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/0ae240e6276d9da6cd5c362b0e477962ece2e997-1.rds`.
[2025-04-24 01:07:03] [INFO]    [OmnipathR] Download ready [key=0ae240e6276d9da6cd5c362b0e477962ece2e997, version=1]
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:03] [INFO]    [OmnipathR] Cache item `0ae240e6276d9da6cd5c362b0e477962ece2e997` version 1: status changed from `started` to `ready`.
[2025-04-24 01:07:03] [SUCCESS] [OmnipathR] Downloaded 3310 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=LRdb,query_type=interactions]
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:07:03] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:07:04] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:07:04] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:04] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:04] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/0ae240e6276d9da6cd5c362b0e477962ece2e997-1.rds`.
[2025-04-24 01:07:04] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:04] [SUCCESS] [OmnipathR] Loaded 3310 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:07:04] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:07:04] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=LRdb,query_type=interactions]
[2025-04-24 01:07:04] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:07:04] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:07:05] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:07:05] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:05] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:05] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/0ae240e6276d9da6cd5c362b0e477962ece2e997-1.rds`.
[2025-04-24 01:07:05] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:05] [SUCCESS] [OmnipathR] Loaded 3310 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:07:05] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:07:05] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=LRdb,query_type=interactions]
[2025-04-24 01:07:05] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:07:05] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:07:06] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:07:06] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:06] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:06] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/0ae240e6276d9da6cd5c362b0e477962ece2e997-1.rds`.
[2025-04-24 01:07:06] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=LRdb&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:06] [SUCCESS] [OmnipathR] Loaded 3310 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:07:06] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:07:06] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=iTALK,query_type=interactions]
[2025-04-24 01:07:06] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:07:06] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:07] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:07] [INFO]    [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:07] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] HTTP request by `omnipath_curl`.
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] The following curl options are not available: tcp_keepcnt
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=<function>,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=1,ssl_verifyhost=2]
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] HTTP v1 GET: status 200.
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] Downloaded 15.7 Kb in 0.305811s from omnipathdb.org (51.2 Kb/s); Redirect: 0s, DNS look up: 0.001968s, Connection: 0.002718s, Pretransfer: 0.151358s, First byte at: 0.305262s
[2025-04-24 01:07:07] [TRACE]   [OmnipathR] HTTP headers: HTTP/1.1 200 OK; Server: nginx; Date: Thu, 24 Apr 2025 05:07:07 GMT; Content-Type: text/plain; charset=utf-8; Transfer-Encoding: chunked; Connection: keep-alive; Cache-Control: max-age=3600; Access-Control-Allow-Origin: *; Expires: Thu, 24 Apr 2025 06:07:07 GMT; Cache-Control: public; X-Frame-Options: DENY; Content-Encoding: gzip
[2025-04-24 01:07:08] [INFO]    [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:08] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:07:08] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:08] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:07:08] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:08] [INFO]    [OmnipathR] Cache item `b5d1617be0762d096dbf001209e826bff4794c4d` version 1: status changed from `unknown` to `started`.
[2025-04-24 01:07:08] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/biocbuild/.cache/OmnipathR/b5d1617be0762d096dbf001209e826bff4794c4d-1.rds`.
[2025-04-24 01:07:09] [TRACE]   [OmnipathR] Exported RDS to `/home/biocbuild/.cache/OmnipathR/b5d1617be0762d096dbf001209e826bff4794c4d-1.rds`.
[2025-04-24 01:07:09] [INFO]    [OmnipathR] Download ready [key=b5d1617be0762d096dbf001209e826bff4794c4d, version=1]
[2025-04-24 01:07:09] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:07:09] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:09] [INFO]    [OmnipathR] Cache item `b5d1617be0762d096dbf001209e826bff4794c4d` version 1: status changed from `started` to `ready`.
[2025-04-24 01:07:09] [SUCCESS] [OmnipathR] Downloaded 2639 interactions.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:07:09] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:07:09] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=iTALK,query_type=interactions]
[2025-04-24 01:07:09] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:07:09] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:07:09] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:07:09] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:10] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:10] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/b5d1617be0762d096dbf001209e826bff4794c4d-1.rds`.
[2025-04-24 01:07:10] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:10] [SUCCESS] [OmnipathR] Loaded 2639 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:07:10] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:07:10] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=iTALK,query_type=interactions]
[2025-04-24 01:07:10] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:07:10] [TRACE]   [OmnipathR] Orthology targets: 
Warning in readLines(con = path, encoding = encoding) :
  incomplete final line found on 'https://omnipathdb.org/resources'
[2025-04-24 01:07:11] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2025-04-24 01:07:11] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:07:11] [TRACE]   [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:11] [TRACE]   [OmnipathR] Loaded data from RDS `/home/biocbuild/.cache/OmnipathR/b5d1617be0762d096dbf001209e826bff4794c4d-1.rds`.
[2025-04-24 01:07:11] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=iTALK&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2025-04-24 01:07:11] [SUCCESS] [OmnipathR] Loaded 2639 interactions from cache.
Warning in import_post_translational_interactions(resources = resource) :
  'import_post_translational_interactions' is deprecated.
Use 'post_translational' instead.
See help("Deprecated")
[2025-04-24 01:07:11] [TRACE]   [OmnipathR] Processing args for OmniPath query
[2025-04-24 01:07:11] [TRACE]   [OmnipathR] Arguments for OmniPath query: [resources=iTALK,query_type=interactions]
[2025-04-24 01:07:11] [TRACE]   [OmnipathR] Organism(s): 9606
[2025-04-24 01:07:11] [TRACE]   [OmnipathR] Orthology targets: 
Warning in file(con, "r") :
  URL 'https://omnipathdb.org/resources': status was 'Server returned nothing (no headers, no data)'
Error in `map()`:
ℹ In index: 16.
Caused by error in `map()`:
ℹ In index: 4.
Caused by error in `map()`:
ℹ In index: 1.
Caused by error in `file()`:
! cannot open the connection to 'https://omnipathdb.org/resources'
Backtrace:
     ▆
  1. ├─OmnipathR::curated_ligrec_stats()
  2. │ └─... %>% unnest_wider(col = data)
  3. ├─OmnipathR:::unnest_wider(., col = data)
  4. │ └─base::eval(call[[tbl_name]], parent.frame())
  5. │   └─base::eval(call[[tbl_name]], parent.frame())
  6. ├─tibble::tibble(resource = names(.), data = .)
  7. │ └─tibble:::tibble_quos(xs, .rows, .name_repair)
  8. │   └─rlang::eval_tidy(xs[[j]], mask)
  9. ├─rlang::set_names(map(., stats_one_resource, curated), .)
 10. ├─purrr::map(., stats_one_resource, curated)
 11. │ └─purrr:::map_("list", .x, .f, ..., .progress = .progress)
 12. │   ├─purrr:::with_indexed_errors(...)
 13. │   │ └─base::withCallingHandlers(...)
 14. │   ├─purrr:::call_with_cleanup(...)
 15. │   └─OmnipathR (local) .f(.x[[i]], ...)
 16. │     └─... %>% ...
 17. ├─purrr::map(., nrow)
 18. │ └─purrr:::map_("list", .x, .f, ..., .progress = .progress)
 19. │   └─purrr:::vctrs_vec_compat(.x, .purrr_user_env)
 20. ├─rlang::set_names(...)
 21. ├─purrr::map(...)
 22. │ └─purrr:::map_("list", .x, .f, ..., .progress = .progress)
 23. │   ├─purrr:::with_indexed_errors(...)
 24. │   │ └─base::withCallingHandlers(...)
 25. │   ├─purrr:::call_with_cleanup(...)
 26. │   └─OmnipathR (local) .f(.x[[i]], ...)
 27. │     └─get(sprintf("%s_one_resource", field))(resource, curated)
 28. │       └─OmnipathR:::literature_one_resource(resource = resource)
 29. │         ├─... %>% with_references(resources = resource)
 30. │         └─OmnipathR::import_post_translational_interactions(resources = resource)
 31. │           └─OmnipathR::post_translational(...)
 32. │             ├─rlang::exec(omnipath_query, !!!args)
 33. │             └─OmnipathR (local) `<fn>`(resources = "iTALK", query_type = "interactions", datasets = `<chr>`)
 34. │               └─environment() %>% as.list %>% c(list(...)) %>% ...
 35. ├─OmnipathR::with_references(., resources = resource)
 36. │ └─... %>% distinct(across(everything()))
 37. ├─dplyr::distinct(., across(everything()))
 38. ├─dplyr::bind_rows(.)
 39. │ └─rlang::list2(...)
 40. ├─purrr::map(., .with_references, data = data)
 41. │ └─purrr:::map_("list", .x, .f, ..., .progress = .progress)
 42. │   ├─purrr:::with_indexed_errors(...)
 43. │   │ └─base::withCallingHandlers(...)
 44. │   ├─purrr:::call_with_cleanup(...)
 45. │   └─OmnipathR (local) .f(.x[[i]], ...)
 46. │     └─data %>% filter(predicate(references))
 47. ├─dplyr::filter(., predicate(references))
 48. ├─OmnipathR:::omnipath_check_param(.)
 49. │ └─OmnipathR::resources(param$query_type)
 50. │   └─OmnipathR:::safe_json(path = resources_url)
 51. │     └─base::readLines(con = path, encoding = encoding)
 52. │       └─base::file(con, "r")
 53. └─base::.handleSimpleError(...)
 54.   └─purrr (local) h(simpleError(msg, call))
 55.     └─cli::cli_abort(...)
 56.       └─rlang::abort(...)
Execution halted
Examples with CPU (user + system) or elapsed time > 5s
                                       user system elapsed
annotation_categories                75.265  0.072  76.755
curated_ligand_receptor_interactions  6.510  0.855  16.766
all_uniprots                          1.615  0.322  21.101
annotated_network                     1.437  0.404  26.776
* checking for unstated dependencies in ‘tests’ ... OK
* checking tests ...
  Running ‘testthat.R’
 OK
* checking for unstated dependencies in vignettes ... OK
* checking package vignettes ... OK
* checking re-building of vignette outputs ... OK
* checking PDF version of manual ... OK
* DONE

Status: 1 ERROR, 2 NOTEs
See
  ‘/home/biocbuild/bbs-3.21-bioc/meat/OmnipathR.Rcheck/00check.log’
for details.


Installation output

OmnipathR.Rcheck/00install.out

##############################################################################
##############################################################################
###
### Running command:
###
###   /home/biocbuild/bbs-3.21-bioc/R/bin/R CMD INSTALL OmnipathR
###
##############################################################################
##############################################################################


* installing to library ‘/home/biocbuild/bbs-3.21-bioc/R/site-library’
* installing *source* package ‘OmnipathR’ ...
** this is package ‘OmnipathR’ version ‘3.16.0’
** using staged installation
** R
** inst
** byte-compile and prepare package for lazy loading
** help
*** installing help indices
*** copying figures
** building package indices
** installing vignettes
** testing if installed package can be loaded from temporary location
[2025-04-23 15:13:51] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-23 15:13:51] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:51] [INFO]    [OmnipathR] Initialized cache: `/home/biocbuild/.cache/OmnipathR`.
[2025-04-23 15:13:51] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-04-23 15:13:51] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-04-23
[2025-04-23 15:13:51] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.5.0; ; 2025-04-23 19:13:37 UTC; unix
[2025-04-23 15:13:51] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.16.0
[2025-04-23 15:13:51] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.21
[2025-04-23 15:13:52] [INFO]    [OmnipathR] Session info: [version=R version 4.5.0 RC (2025-04-04 r88126); os=Ubuntu 24.04.2 LTS; system=x86_64, linux-gnu; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-04-23; pandoc=2.7.3 @ /usr/bin/ (via rmarkdown); quarto=1.5.57 @ /usr/local/bin/quarto]
[2025-04-23 15:13:52] [INFO]    [OmnipathR] External libraries: [cairo=1.18.0; cairoFT=; pango=1.52.1; png=1.6.43; jpeg=8.0; tiff=LIBTIFF, Version 4.5.1; tcl=8.6.14; curl=8.5.0; zlib=1.3; bzlib=1.0.8, 13-Jul-2019; xz=5.4.5; deflate=1.19; PCRE=10.42 2022-12-11; ICU=74.2; TRE=TRE 0.8.0 R_fixes (BSD); iconv=glibc 2.39; readline=8.2; BLAS=/home/biocbuild/bbs-3.21-bioc/R/lib/libRblas.so; lapack=/usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0; lapack_version=3.12.0]
[2025-04-23 15:13:52] [INFO]    [OmnipathR] Loaded packages: backports 1.5.0(2024-05-23); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.2(2024-07-29); chromote 0.5.0(2025-03-21); cli 3.6.5(2025-04-23); crayon 1.5.3(2024-06-20); curl 6.2.2(2025-03-24); DBI 1.2.3(2024-06-02); digest 0.6.37(2024-08-19); dplyr 1.1.4(2023-11-17); evaluate 1.0.3(2025-01-10); fastmap 1.2.0(2024-05-15); fs 1.6.6(2025-04-12); generics 0.1.3(2022-07-05); glue 1.8.0(2024-09-30); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.1.2(2025-03-26); igraph 2.1.4(2025-01-23); jsonlite 2.0.0(2025-03-27); knitr 1.50(2025-03-16); later 1.4.2(2025-04-08); lifecycle 1.0.4(2023-11-07); logger 0.4.0(2024-10-22); lubridate 1.9.4(2024-12-08); magrittr 2.0.3(2022-03-30); memoise 2.0.1(2021-11-26); OmnipathR 3.16.0(2025-04-23); pillar 1.10.2(2025-04-05); pkgconfig 2.0.3(2019-09-22); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.2(2024-11-28); ps 1.9.1(2025-04-12); purrr 1.0.4(2025-02-05); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.0(2024-11-01); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.0.14(2025-01-12); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); RSQLite 2.3.9(2024-12-03); rvest 1.0.4(2024-02-12); sessioninfo 1.2.3(2025-02-05); stringi 1.8.7(2025-03-27); stringr 1.5.1(2023-11-14); tibble 3.2.1(2023-03-20); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.52(2025-04-02); XML 3.99-0.18(2025-01-01); xml2 1.3.8(2025-03-14); yaml 2.3.10(2024-07-26); zip 2.3.2(2025-02-01)
[2025-04-23 15:13:52] [INFO]    [OmnipathR] CURL: version: 8.5.0; headers: 8.5.0; ssl_version: OpenSSL/3.0.13; libz_version: 1.3; libssh_version: libssh/0.10.6/openssl/zlib; libidn_version: 2.3.7; host: x86_64-pc-linux-gnu; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtmp, rtmpe, rtmps, rtmpt, rtmpte, rtmpts, rtsp, scp, sftp, smb, smbs, smtp, smtps, telnet, tftp; ipv6: TRUE; http2: TRUE; idn: TRUE; url_parser: TRUE
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] Cache is at `/home/biocbuild/.cache/OmnipathR`.
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] Contains 8 files.
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:52] [SUCCESS] [OmnipathR] Removing all cache contents from `/home/biocbuild/.cache/OmnipathR`.
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] Pandoc version: `2.7.3`.
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/00LOCK-OmnipathR/00new/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/00LOCK-OmnipathR/00new/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/00LOCK-OmnipathR/00new/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/00LOCK-OmnipathR/00new/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:52] [TRACE]   [OmnipathR] Cache locked: FALSE
** testing if installed package can be loaded from final location
[2025-04-23 15:13:54] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-23 15:13:54] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:54] [INFO]    [OmnipathR] Initialized cache: `/home/biocbuild/.cache/OmnipathR`.
[2025-04-23 15:13:54] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-04-23 15:13:54] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-04-23
[2025-04-23 15:13:54] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.5.0; ; 2025-04-23 19:13:37 UTC; unix
[2025-04-23 15:13:54] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.16.0
[2025-04-23 15:13:54] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.21
[2025-04-23 15:13:55] [INFO]    [OmnipathR] Session info: [version=R version 4.5.0 RC (2025-04-04 r88126); os=Ubuntu 24.04.2 LTS; system=x86_64, linux-gnu; ui=X11; language=(EN); collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-04-23; pandoc=2.7.3 @ /usr/bin/ (via rmarkdown); quarto=1.5.57 @ /usr/local/bin/quarto]
[2025-04-23 15:13:55] [INFO]    [OmnipathR] External libraries: [cairo=1.18.0; cairoFT=; pango=1.52.1; png=1.6.43; jpeg=8.0; tiff=LIBTIFF, Version 4.5.1; tcl=8.6.14; curl=8.5.0; zlib=1.3; bzlib=1.0.8, 13-Jul-2019; xz=5.4.5; deflate=1.19; PCRE=10.42 2022-12-11; ICU=74.2; TRE=TRE 0.8.0 R_fixes (BSD); iconv=glibc 2.39; readline=8.2; BLAS=/home/biocbuild/bbs-3.21-bioc/R/lib/libRblas.so; lapack=/usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0; lapack_version=3.12.0]
[2025-04-23 15:13:55] [INFO]    [OmnipathR] Loaded packages: backports 1.5.0(2024-05-23); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.2(2024-07-29); chromote 0.5.0(2025-03-21); cli 3.6.5(2025-04-23); crayon 1.5.3(2024-06-20); curl 6.2.2(2025-03-24); DBI 1.2.3(2024-06-02); digest 0.6.37(2024-08-19); dplyr 1.1.4(2023-11-17); evaluate 1.0.3(2025-01-10); fastmap 1.2.0(2024-05-15); fs 1.6.6(2025-04-12); generics 0.1.3(2022-07-05); glue 1.8.0(2024-09-30); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.1.2(2025-03-26); igraph 2.1.4(2025-01-23); jsonlite 2.0.0(2025-03-27); knitr 1.50(2025-03-16); later 1.4.2(2025-04-08); lifecycle 1.0.4(2023-11-07); logger 0.4.0(2024-10-22); lubridate 1.9.4(2024-12-08); magrittr 2.0.3(2022-03-30); memoise 2.0.1(2021-11-26); OmnipathR 3.16.0(2025-04-23); pillar 1.10.2(2025-04-05); pkgconfig 2.0.3(2019-09-22); prettyunits 1.2.0(2023-09-24); processx 3.8.6(2025-02-21); progress 1.2.3(2023-12-06); promises 1.3.2(2024-11-28); ps 1.9.1(2025-04-12); purrr 1.0.4(2025-02-05); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.0(2024-11-01); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.0.14(2025-01-12); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); RSQLite 2.3.9(2024-12-03); rvest 1.0.4(2024-02-12); sessioninfo 1.2.3(2025-02-05); stringi 1.8.7(2025-03-27); stringr 1.5.1(2023-11-14); tibble 3.2.1(2023-03-20); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); websocket 1.4.4(2025-04-10); withr 3.0.2(2024-10-28); xfun 0.52(2025-04-02); XML 3.99-0.18(2025-01-01); xml2 1.3.8(2025-03-14); yaml 2.3.10(2024-07-26); zip 2.3.2(2025-02-01)
[2025-04-23 15:13:55] [INFO]    [OmnipathR] CURL: version: 8.5.0; headers: 8.5.0; ssl_version: OpenSSL/3.0.13; libz_version: 1.3; libssh_version: libssh/0.10.6/openssl/zlib; libidn_version: 2.3.7; host: x86_64-pc-linux-gnu; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtmp, rtmpe, rtmps, rtmpt, rtmpte, rtmpts, rtsp, scp, sftp, smb, smbs, smtp, smtps, telnet, tftp; ipv6: TRUE; http2: TRUE; idn: TRUE; url_parser: TRUE
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] Cache is at `/home/biocbuild/.cache/OmnipathR`.
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] Contains 1 files.
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:55] [SUCCESS] [OmnipathR] Removing all cache contents from `/home/biocbuild/.cache/OmnipathR`.
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] Pandoc version: `2.7.3`.
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-23 15:13:55] [TRACE]   [OmnipathR] Cache locked: FALSE
** testing if installed package keeps a record of temporary installation path
* DONE (OmnipathR)

Tests output

OmnipathR.Rcheck/tests/testthat.Rout


R version 4.5.0 RC (2025-04-04 r88126) -- "How About a Twenty-Six"
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Platform: x86_64-pc-linux-gnu

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> #!/usr/bin/env Rscript
> 
> #
> #  This file is part of the `OmnipathR` R package
> #
> #  Copyright
> #  2018-2024
> #  Saez Lab, Uniklinik RWTH Aachen, Heidelberg University
> #
> #  File author(s): Alberto Valdeolivas
> #                  Dénes Türei (turei.denes@gmail.com)
> #                  Attila Gábor
> #
> #  Distributed under the MIT (Expat) License.
> #  See accompanying file `LICENSE` or find a copy at
> #      https://directory.fsf.org/wiki/License:Expat
> #
> #  Website: https://r.omnipathdb.org/
> #  Git repo: https://github.com/saezlab/OmnipathR
> #
> 
> 
> library(testthat)
> library(OmnipathR)
[2025-04-24 01:08:29] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:08:29] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:08:29] [INFO]    [OmnipathR] Initialized cache: `/home/biocbuild/.cache/OmnipathR`.
[2025-04-24 01:08:29] [INFO]    [OmnipathR] Package `OmnipathR` packaged: NA
[2025-04-24 01:08:29] [INFO]    [OmnipathR] Package `OmnipathR` date/publication: 2025-04-23
[2025-04-24 01:08:29] [INFO]    [OmnipathR] Package `OmnipathR` built: R 4.5.0; ; 2025-04-23 19:13:37 UTC; unix
[2025-04-24 01:08:29] [INFO]    [OmnipathR] Package `OmnipathR` version: 3.16.0
[2025-04-24 01:08:29] [INFO]    [OmnipathR] Package `OmnipathR` repository: Bioconductor 3.21
[2025-04-24 01:08:29] [INFO]    [OmnipathR] Session info: [version=R version 4.5.0 RC (2025-04-04 r88126); os=Ubuntu 24.04.2 LTS; system=x86_64, linux-gnu; ui=X11; language=C; collate=C; ctype=en_US.UTF-8; tz=America/New_York; date=2025-04-24; pandoc=2.7.3 @ /usr/bin/ (via rmarkdown); quarto=1.5.57 @ /usr/local/bin/quarto]
[2025-04-24 01:08:29] [INFO]    [OmnipathR] External libraries: [cairo=1.18.0; cairoFT=; pango=1.52.1; png=1.6.43; jpeg=8.0; tiff=LIBTIFF, Version 4.5.1; tcl=8.6.14; curl=8.5.0; zlib=1.3; bzlib=1.0.8, 13-Jul-2019; xz=5.4.5; deflate=1.19; PCRE=10.42 2022-12-11; ICU=74.2; TRE=TRE 0.8.0 R_fixes (BSD); iconv=glibc 2.39; readline=8.2; BLAS=/home/biocbuild/bbs-3.21-bioc/R/lib/libRblas.so; lapack=/usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0; lapack_version=3.12.0]
[2025-04-24 01:08:30] [INFO]    [OmnipathR] Loaded packages: backports 1.5.0(2024-05-23); bit 4.6.0(2025-03-06); bit64 4.6.0-1(2025-01-16); blob 1.2.4(2023-03-17); brio 1.1.5(2024-04-24); cachem 1.1.0(2024-05-16); cellranger 1.1.0(2016-07-27); checkmate 2.3.2(2024-07-29); cli 3.6.5(2025-04-23); crayon 1.5.3(2024-06-20); curl 6.2.2(2025-03-24); DBI 1.2.3(2024-06-02); digest 0.6.37(2024-08-19); dplyr 1.1.4(2023-11-17); evaluate 1.0.3(2025-01-10); fastmap 1.2.0(2024-05-15); fs 1.6.6(2025-04-12); generics 0.1.3(2022-07-05); glue 1.8.0(2024-09-30); hms 1.1.3(2023-03-21); htmltools 0.5.8.1(2024-04-04); httr 1.4.7(2023-08-15); httr2 1.1.2(2025-03-26); igraph 2.1.4(2025-01-23); jsonlite 2.0.0(2025-03-27); knitr 1.50(2025-03-16); later 1.4.2(2025-04-08); lifecycle 1.0.4(2023-11-07); logger 0.4.0(2024-10-22); lubridate 1.9.4(2024-12-08); magrittr 2.0.3(2022-03-30); memoise 2.0.1(2021-11-26); OmnipathR 3.16.0(2025-04-23); pillar 1.10.2(2025-04-05); pkgconfig 2.0.3(2019-09-22); prettyunits 1.2.0(2023-09-24); progress 1.2.3(2023-12-06); purrr 1.0.4(2025-02-05); R.methodsS3 1.8.2(2022-06-13); R.oo 1.27.0(2024-11-01); R.utils 2.13.0(2025-02-24); R6 2.6.1(2025-02-15); rappdirs 0.3.3(2021-01-31); Rcpp 1.0.14(2025-01-12); readr 2.1.5(2024-01-10); readxl 1.4.5(2025-03-07); rlang 1.1.6(2025-04-11); rmarkdown 2.29(2024-11-04); RSQLite 2.3.9(2024-12-03); rvest 1.0.4(2024-02-12); sessioninfo 1.2.3(2025-02-05); stringi 1.8.7(2025-03-27); stringr 1.5.1(2023-11-14); testthat 3.2.3(2025-01-13); tibble 3.2.1(2023-03-20); tidyr 1.3.1(2024-01-24); tidyselect 1.2.1(2024-03-11); timechange 0.3.0(2024-01-18); tzdb 0.5.0(2025-03-15); vctrs 0.6.5(2023-12-01); withr 3.0.2(2024-10-28); xfun 0.52(2025-04-02); XML 3.99-0.18(2025-01-01); xml2 1.3.8(2025-03-14); yaml 2.3.10(2024-07-26); zip 2.3.2(2025-02-01)
[2025-04-24 01:08:30] [INFO]    [OmnipathR] CURL: version: 8.5.0; headers: 8.5.0; ssl_version: OpenSSL/3.0.13; libz_version: 1.3; libssh_version: libssh/0.10.6/openssl/zlib; libidn_version: 2.3.7; host: x86_64-pc-linux-gnu; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtmp, rtmpe, rtmps, rtmpt, rtmpte, rtmpts, rtsp, scp, sftp, smb, smbs, smtp, smtps, telnet, tftp; ipv6: TRUE; http2: TRUE; idn: TRUE; url_parser: TRUE
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] Cache is at `/home/biocbuild/.cache/OmnipathR`.
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] Contains 33 files.
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:08:30] [SUCCESS] [OmnipathR] Removing all cache contents from `/home/biocbuild/.cache/OmnipathR`.
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] Pandoc version: `2.7.3`.
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] Reading JSON from `/home/biocbuild/bbs-3.21-bioc/R/site-library/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2025-04-24 01:08:30] [TRACE]   [OmnipathR] Cache locked: FALSE
> 
> test_check('OmnipathR')
[ FAIL 0 | WARN 11 | SKIP 0 | PASS 38 ]

[ FAIL 0 | WARN 11 | SKIP 0 | PASS 38 ]
> 
> proc.time()
   user  system elapsed 
 25.878   3.077 157.877 

Example timings

OmnipathR.Rcheck/OmnipathR-Ex.timings

nameusersystemelapsed
OmnipathR0.0000.0000.001
all_uniprot_acs0.0150.0010.016
all_uniprots 1.615 0.32221.101
ancestors0.0080.0010.010
annotated_network 1.437 0.40426.776
annotation_categories75.265 0.07276.755
annotation_resources0.1680.0160.964
annotations0.6470.0981.578
biomart_query1.0090.0512.009
bioplex10.0090.0010.009
bioplex20.0070.0010.008
bioplex30.0060.0010.008
bioplex_all0.0070.0010.008
bioplex_hct116_10.0070.0010.007
bma_motif_es0.6810.0731.694
bma_motif_vs0.2080.0040.924
chalmers_gem0.0090.0000.009
chalmers_gem_id_mapping_table0.0080.0000.008
chalmers_gem_id_type0.0020.0000.002
chalmers_gem_metabolites0.0080.0000.008
chalmers_gem_network0.0090.0000.008
chalmers_gem_raw0.0080.0000.008
chalmers_gem_reactions0.0070.0010.008
common_name0.0300.0010.031
complex_genes0.7150.0302.642
complex_resources0.1710.0050.823
complexes0.2360.0040.908
consensuspathdb_download000
consensuspathdb_raw_table0.0070.0010.008
cosmos_pkn000
curated_ligand_receptor_interactions 6.510 0.85516.766