---
title: "Bioconductor style for HTML documents"
author: "Andrzej OleÅ›, Wolfgang Huber, Martin Morgan"
date: "`r doc_date()`"
package: "`r pkg_ver('BiocStyle')`"
abstract: >
  Instructions on enabling _Bioconductor_ style 
  in your _R_ markdown vignettes.
vignette: >
  %\VignetteIndexEntry{Bioconductor style for HTML documents}
  %\VignetteEngine{knitr::rmarkdown}
  %\VignetteEncoding{UTF-8}
output: 
  BiocStyle::html_document
---

# Prerequisites

In order to build .Rmd documents the `r CRANpkg("rmarkdown")` package is necessary, which relies on [pandoc](http://johnmacfarlane.net/pandoc/) to compile the final output document. If you are working within a recent version of RStudio then both rmarkdown and pandoc should be already installed.

If you are missing the `r CRANpkg("rmarkdown")` package then you can install it from CRAN using

```{r rmarkdown, eval=FALSE}
install.packages("rmarkdown")
```

In this case a recent version of [pandoc](http://johnmacfarlane.net/pandoc/) (>= 1.12.3) is also required. See the [pandoc installation instructions](https://github.com/rstudio/rmarkdown/blob/master/PANDOC.md) for details on installing pandoc for your platform.


# Authoring R markdown HTML package vignettes

To enable the _Bioconductor_ style in your markdown (`.Rmd`) vignettes you need to:

- Edit to the `DESCRIPTION` file by adding

        VignetteBuilder: knitr
        Suggests: BiocStyle, knitr, rmarkdown

- Specify `BiocStyle::html_document` as the output format and add vignette metadata in the document header:

        ---
        title: "Vignette Title"
        author: "Vignette Author"
        output: 
          BiocStyle::html_document
        vignette: >
          %\VignetteIndexEntry{Vignette Title}
          %\VignetteEngine{knitr::rmarkdown}
          %\VignetteEncoding{UTF-8}  
        ---

The `vignette` section is required in order to instruct R how to build the vignette. Note that the `\VignetteIndexEntry` should match the `title` of your vignette.
  
It is also possible to specify additional details such as:

- document compilation `date` inserted using the helper function `doc_date`
- `package` version specification added by `pkg_ver`
- vignette `abstract`
    
as in the following example. Note the inclusion of an additional style sheet `custom.css` by specifying it in the document header.

```{r code, echo = FALSE}
## The following redefinitions are only for printing the verbatim header below
doc_date = function() "`r doc_date()`"
pkg_ver = function(name) sprintf("`r pkg_ver('%s')`", name)
```

    ---
    title: "Vignette Title"
    author: "Vignette Author"
    date: "`r doc_date()`"
    package: "`r pkg_ver('BiocStyle')`"
    abstract: >
      Vignette Abstract
    vignette: >
      %\VignetteIndexEntry{Vignette Title}
      %\VignetteEngine{knitr::rmarkdown}
      %\VignetteEncoding{UTF-8}
    output: 
      BiocStyle::html_document:
        css: custom.css
    ---


## Use with R markdown v1

Apart from the default markdown engine implemented in the `r CRANpkg('rmarkdown')` package,
it is also possible to compile Bioconductor documents using the older markdown v1 engine 
from the package `r CRANpkg('markdown')`. There are some
differences in setup and the resulting output between these two
engines. 

To use the `r CRANpkg('markdown')` vignette builder engine:

- Add the following to the `DESCRIPTION` file

        VignetteBuilder: knitr
        Suggests: BiocStyle, knitr
        
- Specify the vignette engine in the `.Rmd` files (inside HTML
  comments)

        <!--
        %% \VignetteEngine{knitr::knitr}
        -->

- Add the following code chunk at the beginning of your `.Rmd`
  vignettes

        ```{r style, echo = FALSE, results = 'asis'}`r ''`
        BiocStyle::markdown()
        ```

The way of attaching CSS files when using
`r CRANpkg('markdown')` differs from how this done with `r CRANpkg('rmarkdown')`.
In the former case additional style sheets can be
used by providing them to the `BiocStyle::markdown` function.
To include `custom.css` file use

    ```{r style, echo = FALSE, results = 'asis'}`r ''`
    BiocStyle::markdown(css.files = c('custom.css'))
    ```


# Style macros

```{r macro, echo=FALSE}
macro <- function(name, pkg, description)
    sprintf('`` `r %s("%s")` `` %s %s', name, pkg,
            description, do.call(name, list(pkg)))
```

`r Biocpkg("BiocStyle")` introduces the following macros useful when
referring to _R_ packages:

* `r macro("Biocpkg", "IRanges", "for _Bioconductor_ software, annotation and experiment data packages,
  including a link to the release landing page or if the package is only in devel, to the devel landing page,")`.

* `r macro("CRANpkg", "data.table", "for _R_ packages available on
  CRAN, including a link to the FHCRC CRAN mirror landing page,")`.

* `r macro("Githubpkg", "rstudio/rmarkdown", "for _R_ packages
  available on GitHub, including a link to the package repository,")`.

* `r macro("Rpackage", "MyPkg", "for _R_ packages that are _not_
  available on _Bioconductor_, CRAN or GitHub;")`.


# Additional formatting features

Compared to the default markdown appearance the formatting differences
include:

* Images and tables appear centered, e.g.

    ```{r figure, fig.width=4.0, fig.height=4.4}
    v = seq(0, 60i, length = 1000)
    plot(abs(v)*exp(v), type = "l", col = "Royalblue")
    ``` 
                
* Tables are displayed with striped rows:
    
    ```markdown
    Fruit   | Price
    ------- | -----
    bananas | 1.2
    apples  | 1.0
    oranges | 2.5
    ```
        
    produces

    Fruit   | Price
    ------- | -----
    bananas | 1.2
    apples  | 1.0
    oranges | 2.5

* Paragraph text is justified

* External links open in new browser tab/window

Math symbols can be included in markdown documents. You can write math
expressions the same way you would in `Latex`, except some differences
in escaping them.

- Inline: For inline formulas use `$P(x) = \frac{1}{2}$` or
  `\(P(x) = \frac{1}{2}\)`, which both render as $P(x) = \frac{1}{2}$.

- Standalone: Math can be displayed in a separate line by writing
  `$$P(x) = \frac{1}{2}$$` or `\[P(x) = \frac{1}{2}.\]`, which both
  result in $$P(x) = \frac{1}{2}.$$


# Session info

Here is the output of `sessionInfo()` on the system on which this
document was compiled:

```{r sessionInfo, echo=FALSE}
sessionInfo()
```


[R]: http://r-project.org
[RStudio]: http://www.rstudio.com/