Changes in version 1.3.4 (2022-03-28)                  

  - Made the following significant changes
      - Add parameter removeNoSymbol in the method normalizeCountMatrix
        to filter genes doesn't have SYMBOL.
      - clusterMarkers slot become topMarkers slot, accessors names
        change in the same way.0

                Changes in version 1.1.002 (2021-08-31)                 

  - Made the following significant changes
      - Added an internal function .retrieveClustersNumberK to suggest
        the clusters number to use in lusterCellsInternal().
      - Added suggestedClustersNumber slot in scRNAseq class to retrieve
        this suggested clusters number.
      - Added accessors getSuggestedClustersNumber and
        setSuggestedClustersNumber.
      - Updated all the objects used in examples and tests to have this
        slot.

                Changes in version 0.99.343 (2021-04-09)                

  - Submission to Bioconductor

  - NAMESPACE
    
      - Imported BiocFileCache package and R_user_dir() of tools package
      - Exported new function conclusCacheClear()

  - DESCRIPTION
    
      - Removed LazyData: true.

  - DataFormatting.R
    
      - Added a caching system for retrieveFromGEO()
      - Created conclusCacheClear() to delete the cache
      - Updated documentation

  - loadDataset.R
    
      - Updated documentation
      - Simplified nested "if" in loadDataset.R

  - methods-normalization.R
    
      - Modified the use of getBM to retrieve only genes of the count
        matrix (instead of the all database)

  - test_setters.R/test_getters.R
    
      - Modified documentation for loadDataOrMatrix()
      - Simplified nested "if" in loadDataset.R

  - test_loadData.R
    
      - Adapted the unit tests to the new format of coldata and rowdata

  - test_scRNAseq-methods.R
    
      - Changed the experiment name to "Light_Experience"
      - Used tempdir() for output directory

  - inst
    
      - Added inst/script to generate data on inst/extdata
      - New data generated

  - vignette
    
      - Used tempdir() for output directory
      - Specified other parameters in the first example of runCONCLUS
        for the very small dataset
      - Replaced old paths by new ones