%\VignetteIndexEntry{GGBase overview} %\VignetteKeywords{Genetical genomics,SNP,expression} %\VignettePackage{GGBase} % % NOTE -- ONLY EDIT THE .Rnw FILE!!! The .tex file is % likely to be overwritten. % \documentclass[12pt]{article} \usepackage{amsmath,pstricks} % With MikTeX 2.9, using pstricks also requires using auto-pst-pdf or running % pdflatex will fail. Note that using auto-pst-pdf requires to set environment % variable MIKTEX_ENABLEWRITE18=t on Windows, and to set shell_escape = t in % texmf.cnf for Tex Live on Unix/Linux/Mac. \usepackage{auto-pst-pdf} \usepackage[authoryear,round]{natbib} \usepackage{hyperref} \textwidth=6.2in \textheight=8.5in %\parskip=.3cm \oddsidemargin=.1in \evensidemargin=.1in \headheight=-.3in \newcommand{\scscst}{\scriptscriptstyle} \newcommand{\scst}{\scriptstyle} \newcommand{\Rfunction}[1]{{\texttt{#1}}} \newcommand{\Robject}[1]{{\texttt{#1}}} \newcommand{\Rpackage}[1]{{\textit{#1}}} \newcommand{\Rmethod}[1]{{\texttt{#1}}} \newcommand{\Rfunarg}[1]{{\texttt{#1}}} \newcommand{\Rclass}[1]{{\textit{#1}}} \textwidth=6.2in \bibliographystyle{plainnat} \begin{document} %\setkeys{Gin}{width=0.55\textwidth} \title{GGBase: infrastructure for genetics of gene expression} \author{VJ Carey} \maketitle \section{Introduction} Data representations for genetics of gene expression in humans must be as efficient as possible. Up to Bioconductor 2.1, integrative genomics experiments could be represented by racExSet instances as defined in package GGtools. Genotypes were represented as integers. For Bioconductor 2.8, we have access to the snpStats package of D. Clayton, and we have introduced the smlSet class to represent genetics of gene expression studies with lists of SnpMatrix instances, along with ordinary representations of expression data. \section{Primary class structure, and associated methods} <>= library(GGBase) getClass("smlSet") showMethods(class="smlSet", where="package:GGBase") @ \section{Example data structure} <>= data(smlSet.example) smlSet.example @ \section{SNP location infrastructure} see the newSNPloc vignette \section{Conclusion} The concepts discussed above define the bulk of the tools supporting the \texttt{gwSnpTests} method of GGtools. Consult the vignette of GGtools for more information. \end{document}