CHANGES IN VERSION 1.0.0 ------------------------ NEW FEATURES o readVcf() for reading and parsing VCF files into a SummarizedExperiment o locateVariants() and predictCoding() for identifying amino acid coding changes in nonsynonymous variants o dbSNPFilter() and regionFilter() for filtering variants on membership in dbSNP or on a particular location in the genome o access to PolyPhen and SIFT predictions through keys() , cols() and select() methods. See ?SIFT or ?PolyPhen. BUG FIXES o No changes classified as 'bug fixes' (package under active development)