\name{estimateMethylationBG} \alias{estimateMethylationBG} %- Also NEED an '\alias' for EACH other topic documented here. \title{ Estimate the background levels of Illumina Infinium methylaton microarrays } \description{ Estimate the background levels of Illumina Infinium methylaton microarrays. It is called by function \code{\link{bgAdjustMethylation}} } \usage{ estimateMethylationBG(methyLumiM, separateColor = FALSE, nbin = 1000) } %- maybe also 'usage' for other objects documented here. \arguments{ \item{methyLumiM}{a MethyLumiM object or any eSet object with "methylated" and "unmethylated" data matrix element in the assayData slot } \item{separateColor}{determine whether to separately process two color channels} \item{nbin}{ the number of bins in the histogram used to estimate the mode position of the density } } \details{ The estimation of background level of Infinium methylaton microarray is based on the assumption that the lots of CpG sites are unmethylated, which results in a density mode of the intensities measured by methylated probes. The position of this mode represents the background level. } \value{ a vector of estimated background levels for individual samples. } \references{ } \author{ Pan DU } \seealso{ See Also \code{\link{lumiMethyB}} and \code{\link{bgAdjustMethylation}} } \examples{ data(example.lumiMethy) estimatedBG = estimateMethylationBG(example.lumiMethy) estimatedBG } % Add one or more standard keywords, see file 'KEYWORDS' in the % R documentation directory. \keyword{methods}