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crupR

This is the development version of crupR; to use it, please install the devel version of Bioconductor.

An R package to predict condition-specific enhancers from ChIP-seq data


Bioconductor version: Development (3.21)

An R package that offers a workflow to predict condition-specific enhancers from ChIP-seq data. The prediction of regulatory units is done in four main steps: Step 1 - the normalization of the ChIP-seq counts. Step 2 - the prediction of active enhancers binwise on the whole genome. Step 3 - the condition-specific clustering of the putative active enhancers. Step 4 - the detection of possible target genes of the condition-specific clusters using RNA-seq counts.

Author: Persia Akbari Omgba [cre], Verena Laupert [aut], Martin Vingron [aut]

Maintainer: Persia Akbari Omgba <omgba at molgen.mpg.de>

Citation (from within R, enter citation("crupR")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("crupR")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("crupR")
crupR Vignette HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews DifferentialPeakCalling, FunctionalPrediction, GeneTarget, HistoneModification, PeakDetection, Software
Version 0.99.4
In Bioconductor since BioC 3.21 (R-4.5)
License GPL-3
Depends R (>= 4.4.0)
Imports bamsignals, Rsamtools, GenomicRanges, preprocessCore, randomForest, rtracklayer, GenomeInfoDb, S4Vectors, ggplot2, matrixStats, dplyr, IRanges, GenomicAlignments, GenomicFeatures, TxDb.Mmusculus.UCSC.mm10.knownGene, TxDb.Mmusculus.UCSC.mm9.knownGene, TxDb.Hsapiens.UCSC.hg19.knownGene, TxDb.Hsapiens.UCSC.hg38.knownGene, reshape2, magrittr, stats, utils, grDevices, SummarizedExperiment, BiocParallel, fs, methods
System Requirements
URL https://github.com/akbariomgba/crupR
Bug Reports https://github.com/akbariomgba/crupR/issues
See More
Suggests testthat, BiocStyle, knitr, rmarkdown
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package crupR_0.99.4.tar.gz
Windows Binary (x86_64) crupR_0.99.4.zip (64-bit only)
macOS Binary (x86_64) crupR_0.99.4.tgz
macOS Binary (arm64) crupR_0.99.4.tgz
Source Repository git clone https://git.bioconductor.org/packages/crupR
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/crupR
Bioc Package Browser https://code.bioconductor.org/browse/crupR/
Package Short Url https://bioconductor.org/packages/crupR/
Package Downloads Report Download Stats